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10.1016/j.jhin.2020.07.009 http://scihub22266oqcxt.onion/10.1016/j.jhin.2020.07.009 32652214!7343644!32652214     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32652214&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Hosp+Infect 2020 ; 106 (2): 226-231 Nephropedia Template TP {{tp|p=32652214|t=2020. Factors affecting stability and infectivity of SARS-CoV-2 |pdf=|usr=}}{{32652214}} gab.com Text Factors affecting stability and infectivity of SARS-CoV-2 JO: J Hosp Infect http://www.kidney.de/pget.php?&tw=1&pmid=32652214 #FOAvip BACKGROUND: In late 2019, a novel human coronavirus - severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) - emerged in Wuhan, China. This virus has caused a global pandemic involving more than 200 countries. SARS-CoV-2 is highly adapted to humans and readily transmits from person-to-person. AIM: To investigate the infectivity of SARS-CoV-2 under various environmental and pH conditions. The efficacies of various laboratory virus inactivation methods and home disinfectants against SARS-CoV-2 were investigated. METHODS: The residual virus in dried form or in solution was titrated on to Vero E6 cells on days 0, 1, 3, 5 and 7 after incubation at different temperatures. Viral viability was determined after treatment with various disinfectants and pH solutions at room temperature (20-25(o)C). FINDINGS: SARS-CoV-2 was able to retain viability for 3-5 days in dried form or 7 days in solution at room temperature. SARS-CoV-2 could be detected under a wide range of pH conditions from pH 4 to pH 11 for several days, and for 1-2 days in stool at room temperature but lost 5 logs of infectivity. A variety of commonly used disinfectants and laboratory inactivation procedures were found to reduce viral viability effectively. CONCLUSION: This study demonstrated the stability of SARS-CoV-2 on environmental surfaces, and raises the possibility of faecal-oral transmission. Commonly used fixatives, nucleic acid extraction methods and heat inactivation were found to reduce viral infectivity significantly, which could ensure hospital and laboratory safety during the SARS-CoV-2 pandemic. Twit Text FOAVip Factors affecting stability and infectivity of SARS-CoV-2 ????J Hosp Infect http://www.kidney.de/pget.php?&tw=1&pmid=32652214 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32652214 #FOAvip English Wikipedia <ref>{{Cite pmid|32652214}}</ref> Factors affecting stability and infectivity of SARS-CoV-2 #MMPMID32652214 Chan KH; Sridhar S; Zhang RR; Chu H; Fung AY; Chan G; Chan JF; To KK; Hung IF; Cheng VC; Yuen KY J Hosp Infect 2020[Oct]; 106 (2): 226-231 PMID32652214show ga BACKGROUND: In late 2019, a novel human coronavirus - severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) - emerged in Wuhan, China. This virus has caused a global pandemic involving more than 200 countries. SARS-CoV-2 is highly adapted to humans and readily transmits from person-to-person. AIM: To investigate the infectivity of SARS-CoV-2 under various environmental and pH conditions. The efficacies of various laboratory virus inactivation methods and home disinfectants against SARS-CoV-2 were investigated. METHODS: The residual virus in dried form or in solution was titrated on to Vero E6 cells on days 0, 1, 3, 5 and 7 after incubation at different temperatures. Viral viability was determined after treatment with various disinfectants and pH solutions at room temperature (20-25(o)C). FINDINGS: SARS-CoV-2 was able to retain viability for 3-5 days in dried form or 7 days in solution at room temperature. SARS-CoV-2 could be detected under a wide range of pH conditions from pH 4 to pH 11 for several days, and for 1-2 days in stool at room temperature but lost 5 logs of infectivity. A variety of commonly used disinfectants and laboratory inactivation procedures were found to reduce viral viability effectively. CONCLUSION: This study demonstrated the stability of SARS-CoV-2 on environmental surfaces, and raises the possibility of faecal-oral transmission. Commonly used fixatives, nucleic acid extraction methods and heat inactivation were found to reduce viral infectivity significantly, which could ensure hospital and laboratory safety during the SARS-CoV-2 pandemic. |*Microbial Viability[MESH] |*Virulence[MESH] |*Virus Inactivation[MESH] |Betacoronavirus/*growth & development/*pathogenicity[MESH] |COVID-19[MESH] |China/epidemiology[MESH] |Coronavirus Infections/epidemiology/*physiopathology[MESH] |Humans[MESH] |Pandemics[MESH] |Pneumonia, Viral/epidemiology/*physiopathology[MESH] |SARS-CoV-2[MESH]Factors affecting stability and infectivity of SARS-CoV-2 (epmc).pdf DeepDyve Pubget Overpricing