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10.1007/s10096-020-03976-8

http://scihub22266oqcxt.onion/10.1007/s10096-020-03976-8
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32651736!7351641!32651736
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suck abstract from ncbi


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pmid32651736      Eur+J+Clin+Microbiol+Infect+Dis 2020 ; 39 (12): 2279-2287
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  • Clinical features in 52 patients with COVID-19 who have increased leukocyte count: a retrospective analysis #MMPMID32651736
  • Zhao K; Li R; Wu X; Zhao Y; Wang T; Zheng Z; Zeng S; Ding X; Nie H
  • Eur J Clin Microbiol Infect Dis 2020[Dec]; 39 (12): 2279-2287 PMID32651736show ga
  • Recent reports have showed that a proportion of patients with Coronavirus Disease 2019 (COVID-19) presented elevated leukocyte count. Clinical data about these patients is scarce. We aimed to evaluate the clinical findings of patients with COVID-19 who have increased leukocyte at admission. We retrospectively collected the clinical data on the 52 patients who have increased leukocyte count at admission from the 619 patients with confirmed COVID-19 who had pneumonia with abnormal features on chest CT scan in Renmin Hospital of Wuhan University in Wuhan, China, from February 3 to March 3, 2020. The mean age of the 52 patients with increased leukocyte count was 64.7 (SD 11.4) years, 32 (61.5%) were men and 47 (90.4%) had fever. Compared with the patients with non-increased leukocyte count, the patients with increased leukocyte count were significantly older (P < 0.01), were more likely to have underlying chronic diseases (P < 0.01), more likely to develop critically illness (P < 0.01), more likely to admit to an ICU (P < 0.01), more likely to receive mechanical ventilation (P < 0.01), had higher rate of death (P < 0.01) and the blood levels of neutrophil count and the serum concentrations of CRP and IL-6 were significantly increased, (P < 0.01). The older patients with COVID-19 who had underlying chronic disorders are more likely to develop leukocytosis. These patients are more likely to develop critical illness, with a high admission to an ICU and a high mortality rate.
  • |Aged[MESH]
  • |Betacoronavirus/pathogenicity[MESH]
  • |Biomarkers/blood[MESH]
  • |C-Reactive Protein/metabolism[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Clinical Laboratory Techniques[MESH]
  • |Coronary Disease/blood/*diagnosis/physiopathology[MESH]
  • |Coronavirus Infections/blood/*diagnosis/mortality/therapy[MESH]
  • |Critical Illness[MESH]
  • |Diabetes Mellitus/blood/*diagnosis/physiopathology[MESH]
  • |Female[MESH]
  • |Hospitalization/statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Hypertension/blood/*diagnosis/physiopathology[MESH]
  • |Intensive Care Units[MESH]
  • |Interleukin-6/blood[MESH]
  • |Leukocyte Count[MESH]
  • |Leukocytes/*pathology/virology[MESH]
  • |Leukocytosis/blood/*diagnosis/mortality/therapy[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/blood/*diagnosis/mortality/therapy[MESH]
  • |Respiration, Artificial[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Factors[MESH]
  • |SARS-CoV-2[MESH]
  • |Severity of Illness Index[MESH]


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