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10.3390/jcm9072158

http://scihub22266oqcxt.onion/10.3390/jcm9072158
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32650509!7408951!32650509
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suck abstract from ncbi

pmid32650509      J+Clin+Med 2020 ; 9 (7): ä
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  • Obesity and COVID-19: Oro-Naso-Sensory Perception #MMPMID32650509
  • Khan AS; Hichami A; Khan NA
  • J Clin Med 2020[Jul]; 9 (7): ä PMID32650509show ga
  • Through a recent upsurge of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic, the clinical assessment of most of the coronavirus disease 19 (COVID-19) patients clearly presents a health condition with the loss of oro-naso-sensory (ONS) perception, responsible for the detection of flavor and savor. These changes include anosmia and dysgeusia. In some cases, these clinical manifestations appear even before the general flu-like symptoms, e.g., sore throat, thoracic oppression and fever. There is no direct report available on the loss of these chemical senses in obese COVID-19 patients. Interestingly, obesity has been shown to be associated with low ONS cues. These alterations in obese subjects are due to obesity-induced altered expression of olfacto-taste receptors. Besides, obesity may further aggravate the SARS-CoV-2 infection, as this pathology is associated with a high degree of inflammation/immunosuppression and reduced protection against viral infections. Hence, obesity represents a great risk factor for SARS-CoV-2 infection, as it may hide the viral-associated altered ONS symptoms, thus leading to a high mortality rate in these subjects.
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