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10.2174/1568026620666200710105507 http://scihub22266oqcxt.onion/10.2174/1568026620666200710105507 32648845!ä!32648845 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Top+Med+Chem 2020 ; 20 (24): 2210-2220 Nephropedia Template TP {{tp|p=32648845|t=2020. Therapeutic Targets and Computational Approaches on Drug Development for COVID-19 |pdf=|usr=}}{{32648845}} gab.com Text Therapeutic Targets and Computational Approaches on Drug Development for COVID-19 JO: Curr Top Med Chem http://www.kidney.de/pget.php?&tw=1&pmid=32648845 #FOAvip World Health Organization declared coronavirus disease (COVID-19) caused by SARS coronavirus-2 (SARS-CoV-2) as pandemic. Its outbreak started in China in Dec 2019 and rapidly spread all over the world. SARS-CoV-2 has infected more than 800,000 people and caused about 35,000 deaths so far, moreover, no approved drugs are available to treat COVID-19. Several investigations have been carried out to identify potent drugs for COVID-19 based on drug repurposing, potential novel compounds from ligand libraries, natural products, short peptides, and RNAseq analysis. This review is focused on three different aspects; (i) targets for drug design (ii) computational methods to identify lead compounds and (iii) drugs for COVID-19. It also covers the latest literature on various hit molecules proposed by computational methods and experimental techniques. Twit Text FOAVip Therapeutic Targets and Computational Approaches on Drug Development for COVID-19 ????Curr Top Med Chem http://www.kidney.de/pget.php?&tw=1&pmid=32648845 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32648845 #FOAvip English Wikipedia <ref>{{Cite pmid|32648845}}</ref> Therapeutic Targets and Computational Approaches on Drug Development for COVID-19 #MMPMID32648845 Shanmugam A; Muralidharan N; Velmurugan D; Gromiha MM Curr Top Med Chem 2020[]; 20 (24): 2210-2220 PMID32648845show ga World Health Organization declared coronavirus disease (COVID-19) caused by SARS coronavirus-2 (SARS-CoV-2) as pandemic. Its outbreak started in China in Dec 2019 and rapidly spread all over the world. SARS-CoV-2 has infected more than 800,000 people and caused about 35,000 deaths so far, moreover, no approved drugs are available to treat COVID-19. Several investigations have been carried out to identify potent drugs for COVID-19 based on drug repurposing, potential novel compounds from ligand libraries, natural products, short peptides, and RNAseq analysis. This review is focused on three different aspects; (i) targets for drug design (ii) computational methods to identify lead compounds and (iii) drugs for COVID-19. It also covers the latest literature on various hit molecules proposed by computational methods and experimental techniques. |Antiviral Agents/chemistry/*pharmacology[MESH] |COVID-19[MESH] |COVID-19 Drug Treatment[MESH] |Computational Biology[MESH] |Coronavirus Infections/*drug therapy[MESH] |Drug Design[MESH] |Humans[MESH] |Molecular Docking Simulation[MESH] |Pandemics[MESH] |Pneumonia, Viral/*drug therapy[MESH]Therapeutic Targets and Computational Approaches on Drug Development f(epmc).pdf DeepDyve Pubget Overpricing