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10.1038/s41598-020-68057-4

http://scihub22266oqcxt.onion/10.1038/s41598-020-68057-4
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suck abstract from ncbi


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pmid32647307      Sci+Rep 2020 ; 10 (1): 11336
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  • Different computed tomography patterns of Coronavirus Disease 2019 (COVID-19) between survivors and non-survivors #MMPMID32647307
  • Pan F; Zheng C; Ye T; Li L; Liu D; Li L; Hesketh RL; Yang L
  • Sci Rep 2020[Jul]; 10 (1): 11336 PMID32647307show ga
  • This study aimed to compare the chest computed tomography (CT) findings between survivors and non-survivors with Coronavirus Disease 2019 (COVID-19). Between 12 January 2020 and 20 February 2020, the records of 124 consecutive patients diagnosed with COVID-19 were retrospectively reviewed and divided into survivor (83/124) and non-survivor (41/124) groups. Chest CT findings were qualitatively compared on admission and serial chest CT scans were semi-quantitively evaluated between two groups using curve estimations. On admission, significantly more bilateral (97.6% vs. 73.5%, p = 0.001) and diffuse lesions (39.0% vs. 8.4%, p < 0.001) with higher total CT score (median 10 vs. 4, p < 0.001) were observed in non-survivor group compared with survivor group. Besides, crazy-paving pattern was more predominant in non-survivor group than survivor group (39.0% vs. 12.0%, p < 0.001). From the prediction of curve estimation, in survivor group total CT score increased in the first 20 days reaching a peak of 6 points and then gradually decreased for more than other 40 days (R(2) = 0.545, p < 0.001). In non-survivor group, total CT score rapidly increased over 10 points in the first 10 days and gradually increased afterwards until ARDS occurred with following death events (R(2) = 0.711, p < 0.001). In conclusion, persistent progression with predominant crazy-paving pattern was the major manifestation of COVID-19 in non-survivors. Understanding this CT feature could help the clinical physician to predict the prognosis of the patients.
  • |*Tomography, X-Ray Computed[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*diagnostic imaging/mortality[MESH]
  • |Disease Progression[MESH]
  • |Female[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Lung/*diagnostic imaging[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnostic imaging/mortality[MESH]
  • |Prognosis[MESH]
  • |Retrospective Studies[MESH]
  • |Survivors[MESH]


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