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suck abstract from ncbi


10.3949/ccjm.87a.ccc044

http://scihub22266oqcxt.onion/10.3949/ccjm.87a.ccc044
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32646930!ä!32646930

suck abstract from ncbi


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pmid32646930      Cleve+Clin+J+Med 2020 ; ä (ä): ä
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  • Cytokine release syndrome and the prospects for immunotherapy with COVID-19 Part 2: The role of interleukin 1 #MMPMID32646930
  • Calabrese LH; Calabrese C
  • Cleve Clin J Med 2020[Jul]; ä (ä): ä PMID32646930show ga
  • Interleukin 1 (IL-1) is a potential target of therapy in COVID-19 during the severe respiratory-inflammatory phase ("cytokine release syndrome"), when pulmonary macrophages are hyperactivated, releasing IL-1 and other cytokines. Preliminary evidence indicates that anakinra and canakinumab, drugs that block the action of IL-1 and have a good safety profile, improve the outcomes of patients with COVID-19 cytokine release syndrome. Results from large, randomized clinical trials are pending.
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