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10.1007/s12471-020-01458-2 http://scihub22266oqcxt.onion/10.1007/s12471-020-01458-2 32643071!7341471!32643071     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Neth+Heart+J 2020 ; 28 (7-8): 410-417 Nephropedia Template TP {{tp|p=32643071|t=2020. Cardiac function in relation to myocardial injury in hospitalised patients with COVID-19 |pdf=|usr=}}{{32643071}} gab.com Text Cardiac function in relation to myocardial injury in hospitalised patients with COVID-19 JO: Neth Heart J http://www.kidney.de/pget.php?&tw=1&pmid=32643071 #FOAvip BACKGROUND: Previous studies have reported on myocardial injury in patients with coronavirus infectious disease 19 (COVID-19) defined as elevated cardiac biomarkers. Whether elevated biomarkers truly represent myocardial dysfunction is not known. The aim of this study was to explore the incidence of ventricular dysfunction and assess its relationship with biomarker analyses. METHODS: This cross-sectional study ran from April 1 to May 12, 2020, and consisted of all consecutively admitted patients to the Radboud university medical centre nursing ward for COVID-19. Laboratory assessment included high-sensitivity Troponin T and N?terminal pro-B-type natriuretic peptide (NT-proBNP). Echocardiographic evaluation focused on left and right ventricular systolic function and global longitudinal strain (GLS). RESULTS: In total, 51 patients were included, with a median age of 63 years (range 51-68 years) of whom 80% was male. Troponin T was elevated (>14?ng/l) in 47%, and a clinically relevant Troponin T elevation (10?x URL) was found in three patients (6%). NT-proBNP was elevated (>300?pg/ml) in 24 patients (47%), and in four (8%) the NT-proBNP concentration was >1,000?pg/ml. Left ventricular dysfunction (ejection fraction <52% and/or GLS >-18%) was observed in 27%, while right ventricular dysfunction (TAPSE <17?mm and/or RV S'?< 10?cm/s) was seen in 10%. There was no association between elevated Troponin T or NT-proBNP and left or right ventricular dysfunction. Patients with confirmed pulmonary embolism had normal right ventricular function. CONCLUSIONS: In hospitalised patients, it seems that COVID-19 predominantly affects the respiratory system, while cardiac dysfunction occurs less often. Based on a single echocardiographic evaluation, we found no relation between elevated Troponin T or NT-proBNP, and ventricular dysfunction. Echocardiography has limited value in screening for ventricular dysfunction. Twit Text FOAVip Cardiac function in relation to myocardial injury in hospitalised patients with COVID-19 ????Neth Heart J http://www.kidney.de/pget.php?&tw=1&pmid=32643071 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32643071 #FOAvip English Wikipedia <ref>{{Cite pmid|32643071}}</ref> Cardiac function in relation to myocardial injury in hospitalised patients with COVID-19 #MMPMID32643071 van den Heuvel FMA; Vos JL; Koop Y; van Dijk APJ; Duijnhouwer AL; de Mast Q; van de Veerdonk FL; Bosch F; Kok B; Netea MG; Hoogerwerf J; Hoefsloot W; Tjwa ETTL; de Korte CL; van Kimmenade RRJ; Nijveldt R Neth Heart J 2020[Jul]; 28 (7-8): 410-417 PMID32643071show ga BACKGROUND: Previous studies have reported on myocardial injury in patients with coronavirus infectious disease 19 (COVID-19) defined as elevated cardiac biomarkers. Whether elevated biomarkers truly represent myocardial dysfunction is not known. The aim of this study was to explore the incidence of ventricular dysfunction and assess its relationship with biomarker analyses. METHODS: This cross-sectional study ran from April 1 to May 12, 2020, and consisted of all consecutively admitted patients to the Radboud university medical centre nursing ward for COVID-19. Laboratory assessment included high-sensitivity Troponin T and N?terminal pro-B-type natriuretic peptide (NT-proBNP). Echocardiographic evaluation focused on left and right ventricular systolic function and global longitudinal strain (GLS). RESULTS: In total, 51 patients were included, with a median age of 63 years (range 51-68 years) of whom 80% was male. Troponin T was elevated (>14?ng/l) in 47%, and a clinically relevant Troponin T elevation (10?x URL) was found in three patients (6%). NT-proBNP was elevated (>300?pg/ml) in 24 patients (47%), and in four (8%) the NT-proBNP concentration was >1,000?pg/ml. Left ventricular dysfunction (ejection fraction <52% and/or GLS >-18%) was observed in 27%, while right ventricular dysfunction (TAPSE <17?mm and/or RV S'?< 10?cm/s) was seen in 10%. There was no association between elevated Troponin T or NT-proBNP and left or right ventricular dysfunction. Patients with confirmed pulmonary embolism had normal right ventricular function. CONCLUSIONS: In hospitalised patients, it seems that COVID-19 predominantly affects the respiratory system, while cardiac dysfunction occurs less often. Based on a single echocardiographic evaluation, we found no relation between elevated Troponin T or NT-proBNP, and ventricular dysfunction. Echocardiography has limited value in screening for ventricular dysfunction. äCardiac function in relation to myocardial injury in hospitalised pati(epmc).pdf DeepDyve Pubget Overpricing