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10.1017/S0950268820001569

http://scihub22266oqcxt.onion/10.1017/S0950268820001569
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32641191!7360951!32641191
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suck abstract from ncbi


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pmid32641191      Epidemiol+Infect 2020 ; 148 (ä): e140
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  • Bacillus Calmette-Guerin vaccination and clinical characteristics and outcomes of COVID-19 in Rhode Island, United States: a cohort study #MMPMID32641191
  • Weng CH; Saal A; Butt WW; Bica N; Fisher JQ; Tao J; Chan PA
  • Epidemiol Infect 2020[Jul]; 148 (ä): e140 PMID32641191show ga
  • Coronavirus disease 2019 (COVID-19) has resulted in a global pandemic, and there is limited data on effective therapies. Bacillus Calmette-Guerin (BCG) vaccine, a live-attenuated strain derived from an isolate of Mycobacterium bovis and originally designed to prevent tuberculosis, has shown some efficacy against infection with unrelated pathogens. In this study, we reviewed 120 consecutive adult patients (>/=18 years old) with COVID-19 at a major federally qualified health centre in Rhode Island, United States from 19 March to 29 April 2020. Median age was 39.5 years (interquartile range, 27.0-50.0), 30% were male and 87.5% were Latino/Hispanics. Eighty-two (68.3%) patients had BCG vaccination. Individuals with BCG vaccination were less likely to require hospital admission during the disease course (3.7% vs. 15.8%, P = 0.019). This association remained unchanged after adjusting for demographics and comorbidities (P = 0.017) using multivariate regression analysis. The finding from our study suggests the potential of BCG in preventing more severe COVID-19.
  • |Adult[MESH]
  • |BCG Vaccine/*immunology[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/epidemiology/*immunology[MESH]
  • |Female[MESH]
  • |Hispanic or Latino[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/epidemiology/*immunology[MESH]
  • |Rhode Island/epidemiology[MESH]


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