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10.3399/bjgpopen20X101116

http://scihub22266oqcxt.onion/10.3399/bjgpopen20X101116
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32636204!7465584!32636204
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suck abstract from ncbi


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pmid32636204      BJGP+Open 2020 ; 4 (3): ä
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  • Social distancing, population density, and spread of COVID-19 in England: a longitudinal study #MMPMID32636204
  • Tammes P
  • BJGP Open 2020[Aug]; 4 (3): ä PMID32636204show ga
  • BACKGROUND: The UK government introduced social distancing measures between 16-22 March 2020, aiming to slow down transmission of COVID-19. AIM: To explore the spreading of COVID-19 in relation to population density after the introduction of social distancing measures. DESIGN & SETTING: Longitudinal design with 5-weekly COVID-19 incidence rates per 100 000 people for 149 English Upper Tier Local Authorities (UTLAs), between 16 March and 19 April 2020. METHOD: Multivariable multilevel model to analyse weekly incidence rates per 100 000 people; time was level-1 unit and UTLA level-2 unit. Population density was divided into quartiles. The model included an interaction between week and population density. Potential confounders were percentage aged >/=65, percentage non-white British, and percentage in two highest classes of the National Statistics Socioeconomic Classification. Co-variates were male life expectancy at birth, and COVID-19 prevalence rate per 100 000 people on March 15. Confounders and co-variates were standardised around the mean. RESULTS: Incidence rates per 100 000 people peaked in the week of March 30-April 5, showing higher adjusted incidence rate per 100 000 people (46.2; 95% confidence interval [CI] = 40.6 to 51.8) in most densely populated ULTAs (quartile 4) than in less densely populated ULTAs (quartile 1: 33.3, 95% CI = 27.4 to 37.2; quartile 2: 35.9, 95% CI = 31.6 to 40.1). Thereafter, incidence rate dropped in the most densely populated ULTAs resulting in rate of 22.4 (95% CI = 16.9 to 28.0) in the week of April 13-19; this was lower than in quartiles 1, 2, and 3, respectively 31.4 (95% CI = 26.5 to 36.3), 34.2 (95% CI = 29.9 to 38.5), and 43.2 (95% CI = 39.0 to 47.4). CONCLUSION: After the introduction of social distancing measures, the incidence rates per 100 000 people dropped stronger in most densely populated ULTAs.
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