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Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Transfus+Apher+Sci 2020 ; 59 (5): 102866 Nephropedia Template TP
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First case of convalescent plasma transfusion in a child with COVID-19-associated severe aplastic anemia #MMPMID32636116
Figlerowicz M; Mania A; Lubarski K; Lewandowska Z; Sluzewski W; Derwich K; Wachowiak J; Mazur-Melewska K
Transfus Apher Sci 2020[Oct]; 59 (5): 102866 PMID32636116show ga
We present the case of a six-year-old girl with severe COVID-19, in whom SARS-CoV-2 was successfully eliminated after convalescent plasma transfusion. Children show a variable clinical course of COVID-19, from asymptomatic to critical. In our patient, we diagnosed COVID-19-associated aplastic anemia with severe pancytopenia. The correlation between SARS-CoV-2 infection with aplastic anemia remains unclear. At the beginning of the disease, we used antiviral drugs and immune modulators as therapy but without any positive results. After providing a transfusion of convalescent plasma, the elimination of SARS-CoV-2 was observed. We did not observe any adverse events of this treatment. The girl still has a diagnosis of aplastic anemia and requires specialist therapy.