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10.1016/j.ijantimicag.2020.106077 http://scihub22266oqcxt.onion/10.1016/j.ijantimicag.2020.106077 32634602!7342082!32634602     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32634602&cmd=llinks): Failed to open stream: HTTP request failed! 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Corticosteroid therapy for patients with COVID-19 pneumonia: a before-after study |pdf=|usr=}}{{32634602}} gab.com Text Corticosteroid therapy for patients with COVID-19 pneumonia: a before-after study JO: Int J Antimicrob Agents http://www.kidney.de/pget.php?&tw=1&pmid=32634602 #FOAvip Anti-inflammatory drugs such as corticosteroids may beneficially modulate the host inflammatory response to coronavirus disease 2019 (COVID-19) pneumonia. The aim of this study was to evaluate the impact of addition of corticosteroids to the hospital protocol for treatment of suspected or confirmed COVID-19 pneumonia on rates of death or intensive care unit (ICU) admission. A before-after study was performed to evaluate the effect of addition of corticosteroids to our institution's COVID-19 treatment protocol on hospital mortality. A total of 257 patients with a COVID-19 diagnosis were included in this study between 3 March 2020 and 14 April 2020. As corticosteroids were widely used after 27 March 2020, two periods were considered for the purposes of this study: the 'before' period from 3-20 March 2020 (n = 85); and the 'after' period from 26 March-14 April 2020 (n = 172). The 'after' period was associated with a lower risk of death [adjusted hazard ratio (aHR) = 0.47, 95% confidence interval (CI) 0.23-0.97; P = 0.04] and a lower risk of ICU admission or of death before ICU admission (aHR = 0.37, 95% CI 0.21-0.64; P = 0.0005) by multivariate analysis adjusted for age, National Early Warning score and institutionalisation status. In conclusion, addition of corticosteroids to our institution's COVID-19 treatment protocol was associated with a significant reduction in hospital mortality in the 'after' period. Twit Text FOAVip Corticosteroid therapy for patients with COVID-19 pneumonia: a before-after study ????Int J Antimicrob Agents http://www.kidney.de/pget.php?&tw=1&pmid=32634602 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32634602 #FOAvip English Wikipedia <ref>{{Cite pmid|32634602}}</ref> Corticosteroid therapy for patients with COVID-19 pneumonia: a before-after study #MMPMID32634602 Bani-Sadr F; Hentzien M; Pascard M; N'Guyen Y; Servettaz A; Andreoletti L; Kanagaratnam L; Jolly D Int J Antimicrob Agents 2020[Aug]; 56 (2): 106077 PMID32634602show ga Anti-inflammatory drugs such as corticosteroids may beneficially modulate the host inflammatory response to coronavirus disease 2019 (COVID-19) pneumonia. The aim of this study was to evaluate the impact of addition of corticosteroids to the hospital protocol for treatment of suspected or confirmed COVID-19 pneumonia on rates of death or intensive care unit (ICU) admission. A before-after study was performed to evaluate the effect of addition of corticosteroids to our institution's COVID-19 treatment protocol on hospital mortality. A total of 257 patients with a COVID-19 diagnosis were included in this study between 3 March 2020 and 14 April 2020. As corticosteroids were widely used after 27 March 2020, two periods were considered for the purposes of this study: the 'before' period from 3-20 March 2020 (n = 85); and the 'after' period from 26 March-14 April 2020 (n = 172). The 'after' period was associated with a lower risk of death [adjusted hazard ratio (aHR) = 0.47, 95% confidence interval (CI) 0.23-0.97; P = 0.04] and a lower risk of ICU admission or of death before ICU admission (aHR = 0.37, 95% CI 0.21-0.64; P = 0.0005) by multivariate analysis adjusted for age, National Early Warning score and institutionalisation status. In conclusion, addition of corticosteroids to our institution's COVID-19 treatment protocol was associated with a significant reduction in hospital mortality in the 'after' period. |Adrenal Cortex Hormones/*therapeutic use[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Betacoronavirus/*isolation & purification[MESH] |COVID-19[MESH] |COVID-19 Drug Treatment[MESH] |Coronavirus Infections/*drug therapy/virology[MESH] |Female[MESH] |Hospital Mortality[MESH] |Humans[MESH] |Male[MESH] |Pandemics[MESH] |Pneumonia, Viral/*drug therapy/virology[MESH]Corticosteroid therapy for patients with COVID-19 pneumonia: a before-(epmc).pdf DeepDyve Pubget Overpricing