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10.1016/j.ejphar.2020.173348 http://scihub22266oqcxt.onion/10.1016/j.ejphar.2020.173348 32634438!7334944!32634438     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Eur+J+Pharmacol 2020 ; 883 (ä): 173348 Nephropedia Template TP {{tp|p=32634438|t=2020. Update on therapeutic approaches and emerging therapies for SARS-CoV-2 virus |pdf=|usr=}}{{32634438}} gab.com Text Update on therapeutic approaches and emerging therapies for SARS-CoV-2 virus JO: Eur J Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=32634438 #FOAvip The global pandemic of coronavirus disease 2019 (COVID-19), caused by novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in over 7,273,958 cases with almost over 413,372 deaths worldwide as per the WHO situational report 143 on COVID-19. There are no known treatment regimens with proven efficacy and vaccines thus far, posing an unprecedented challenge to identify effective drugs and vaccines for prevention and treatment. The urgency for its prevention and cure has resulted in an increased number of proposed treatment options. The high rate and volume of emerging clinical trials on therapies for COVID-19 need to be compared and evaluated to provide scientific evidence for effective medical options. Other emerging non-conventional drug discovery techniques such as bioinformatics and cheminformatics, structure-based drug design, network-based methods for prediction of drug-target interactions, artificial intelligence (AI) and machine learning (ML) and phage technique could provide alternative routes to discovering potent Anti-SARS-CoV2 drugs. While drugs are being repurposed and discovered for COVID-19, novel drug delivery systems will be paramount for efficient delivery and avoidance of possible drug resistance. This review describes the proposed drug targets for therapy, and outcomes of clinical trials that have been reported. It also identifies the adopted treatment modalities that are showing promise, and those that have failed as drug candidates. It further highlights various emerging therapies and future strategies for the treatment of COVID-19 and delivery of Anti-SARS-CoV2 drugs. Twit Text FOAVip Update on therapeutic approaches and emerging therapies for SARS-CoV-2 virus ????Eur J Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=32634438 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32634438 #FOAvip English Wikipedia <ref>{{Cite pmid|32634438}}</ref> Update on therapeutic approaches and emerging therapies for SARS-CoV-2 virus #MMPMID32634438 Omolo CA; Soni N; Fasiku VO; Mackraj I; Govender T Eur J Pharmacol 2020[Sep]; 883 (ä): 173348 PMID32634438show ga The global pandemic of coronavirus disease 2019 (COVID-19), caused by novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in over 7,273,958 cases with almost over 413,372 deaths worldwide as per the WHO situational report 143 on COVID-19. There are no known treatment regimens with proven efficacy and vaccines thus far, posing an unprecedented challenge to identify effective drugs and vaccines for prevention and treatment. The urgency for its prevention and cure has resulted in an increased number of proposed treatment options. The high rate and volume of emerging clinical trials on therapies for COVID-19 need to be compared and evaluated to provide scientific evidence for effective medical options. Other emerging non-conventional drug discovery techniques such as bioinformatics and cheminformatics, structure-based drug design, network-based methods for prediction of drug-target interactions, artificial intelligence (AI) and machine learning (ML) and phage technique could provide alternative routes to discovering potent Anti-SARS-CoV2 drugs. While drugs are being repurposed and discovered for COVID-19, novel drug delivery systems will be paramount for efficient delivery and avoidance of possible drug resistance. This review describes the proposed drug targets for therapy, and outcomes of clinical trials that have been reported. It also identifies the adopted treatment modalities that are showing promise, and those that have failed as drug candidates. It further highlights various emerging therapies and future strategies for the treatment of COVID-19 and delivery of Anti-SARS-CoV2 drugs. |*Coronavirus Infections/drug therapy/epidemiology/prevention & control[MESH] |*Pandemics/prevention & control[MESH] |*Pneumonia, Viral/drug therapy/epidemiology/prevention & control[MESH] |Antiviral Agents/*pharmacology[MESH] |Betacoronavirus/drug effects[MESH] |COVID-19[MESH] |Drug Development/*methods[MESH] |Drug Discovery/*methods[MESH] |Humans[MESH]Update on therapeutic approaches and emerging therapies for SARS-CoV-2(epmc).pdf DeepDyve Pubget Overpricing