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10.1038/s41467-020-17317-y http://scihub22266oqcxt.onion/10.1038/s41467-020-17317-y 32632160!7338506!32632160     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32632160&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Commun 2020 ; 11 (1): 3436 Nephropedia Template TP {{tp|p=32632160|t=2020. An evaluation of COVID-19 serological assays informs future diagnostics and exposure assessment |pdf=|usr=}}{{32632160}} gab.com Text An evaluation of COVID-19 serological assays informs future diagnostics and exposure assessment JO: Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=32632160 #FOAvip The world is entering a new era of the COVID-19 pandemic in which there is an increasing call for reliable antibody testing. To support decision making on the deployment of serology for either population screening or diagnostics, we present a detailed comparison of serological COVID-19 assays. We show that among the selected assays there is a wide diversity in assay performance in different scenarios and when correlated to virus neutralizing antibodies. The Wantai ELISA detecting total immunoglobulins against the receptor binding domain of SARS CoV-2, has the best overall characteristics to detect functional antibodies in different stages and severity of disease, including the potential to set a cut-off indicating the presence of protective antibodies. The large variety of available serological assays requires proper assay validation before deciding on deployment of assays for specific applications. Twit Text FOAVip An evaluation of COVID-19 serological assays informs future diagnostics and exposure assessment ????Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=32632160 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32632160 #FOAvip English Wikipedia <ref>{{Cite pmid|32632160}}</ref> An evaluation of COVID-19 serological assays informs future diagnostics and exposure assessment #MMPMID32632160 GeurtsvanKessel CH; Okba NMA; Igloi Z; Bogers S; Embregts CWE; Laksono BM; Leijten L; Rokx C; Rijnders B; Rahamat-Langendoen J; van den Akker JPC; van Kampen JJA; van der Eijk AA; van Binnendijk RS; Haagmans B; Koopmans M Nat Commun 2020[Jul]; 11 (1): 3436 PMID32632160show ga The world is entering a new era of the COVID-19 pandemic in which there is an increasing call for reliable antibody testing. To support decision making on the deployment of serology for either population screening or diagnostics, we present a detailed comparison of serological COVID-19 assays. We show that among the selected assays there is a wide diversity in assay performance in different scenarios and when correlated to virus neutralizing antibodies. The Wantai ELISA detecting total immunoglobulins against the receptor binding domain of SARS CoV-2, has the best overall characteristics to detect functional antibodies in different stages and severity of disease, including the potential to set a cut-off indicating the presence of protective antibodies. The large variety of available serological assays requires proper assay validation before deciding on deployment of assays for specific applications. |Antibodies, Neutralizing/blood[MESH] |Antibodies, Viral/*blood[MESH] |Betacoronavirus[MESH] |COVID-19[MESH] |COVID-19 Testing[MESH] |Clinical Laboratory Techniques[MESH] |Coronavirus Infections/*diagnosis[MESH] |Enzyme-Linked Immunosorbent Assay[MESH] |High-Throughput Screening Assays[MESH] |Humans[MESH] |Luminescent Measurements[MESH] |Neutralization Tests[MESH] |Pandemics[MESH] |Pneumonia, Viral/*diagnosis[MESH] |SARS-CoV-2[MESH] |Sensitivity and Specificity[MESH]An evaluation of COVID-19 serological assays informs future diagnostic(epmc).pdf DeepDyve Pubget Overpricing