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10.1016/j.gene.2020.144944 http://scihub22266oqcxt.onion/10.1016/j.gene.2020.144944 32628976!7833925!32628976     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Gene 2020 ; 758 (ä): 144944 Nephropedia Template TP {{tp|p=32628976|t=2020. SARS-CoV-2 infections and COVID-19 mortalities strongly correlate with ACE1 I/D genotype |pdf=|usr=}}{{32628976}} gab.com Text SARS-CoV-2 infections and COVID-19 mortalities strongly correlate with ACE1 I/D genotype JO: Gene http://www.kidney.de/pget.php?&tw=1&pmid=32628976 #FOAvip Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). The relentless spread and pathogenicity of the virus have become a global public health emergency. One of the striking features of this pandemic is the pronounced impact on specific regions and ethnic groups. In particular, compared with East Asia, where the virus first emerged, SARS-CoV-2 has caused high rates of morbidity and mortality in Europe. This has not been experienced in past global viral infections, such as influenza, severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) and is unique to SARS-CoV-2. For this reason, we investigated the involvement of genetic factors associated with SARS-CoV-2 infection with a focus on angiotensin-converting enzyme (ACE)-related genes, because ACE2 is a receptor for SARS-CoV-2. We found that the ACE1 II genotype frequency in a population was significantly negatively correlated with the number of SARS-CoV-2 cases. Similarly, the ACE1 II genotype was negatively correlated with the number of deaths due to SARS-CoV-2 infection. These data suggest that the ACE1 II genotype may influence the prevalence and clinical outcome of COVID-19 and serve as a predictive marker for COVID-19 risk and severity. Twit Text FOAVip SARS-CoV-2 infections and COVID-19 mortalities strongly correlate with ACE1 I/D genotype ????Gene http://www.kidney.de/pget.php?&tw=1&pmid=32628976 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32628976 #FOAvip English Wikipedia <ref>{{Cite pmid|32628976}}</ref> SARS-CoV-2 infections and COVID-19 mortalities strongly correlate with ACE1 I/D genotype #MMPMID32628976 Yamamoto N; Ariumi Y; Nishida N; Yamamoto R; Bauer G; Gojobori T; Shimotohno K; Mizokami M Gene 2020[Oct]; 758 (ä): 144944 PMID32628976show ga Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). The relentless spread and pathogenicity of the virus have become a global public health emergency. One of the striking features of this pandemic is the pronounced impact on specific regions and ethnic groups. In particular, compared with East Asia, where the virus first emerged, SARS-CoV-2 has caused high rates of morbidity and mortality in Europe. This has not been experienced in past global viral infections, such as influenza, severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) and is unique to SARS-CoV-2. For this reason, we investigated the involvement of genetic factors associated with SARS-CoV-2 infection with a focus on angiotensin-converting enzyme (ACE)-related genes, because ACE2 is a receptor for SARS-CoV-2. We found that the ACE1 II genotype frequency in a population was significantly negatively correlated with the number of SARS-CoV-2 cases. Similarly, the ACE1 II genotype was negatively correlated with the number of deaths due to SARS-CoV-2 infection. These data suggest that the ACE1 II genotype may influence the prevalence and clinical outcome of COVID-19 and serve as a predictive marker for COVID-19 risk and severity. |Angiotensin-Converting Enzyme 2[MESH] |Asia/epidemiology/ethnology[MESH] |Betacoronavirus/metabolism[MESH] |COVID-19[MESH] |Coronavirus Infections/epidemiology/*mortality[MESH] |Europe/epidemiology/ethnology[MESH] |Gene Frequency/genetics[MESH] |Genotype[MESH] |Humans[MESH] |Pandemics[MESH] |Peptidyl-Dipeptidase A/*genetics[MESH] |Pneumonia, Viral/epidemiology/*mortality[MESH] |Polymorphism, Single Nucleotide/genetics[MESH] |Risk[MESH] |Risk Factors[MESH] |SARS-CoV-2[MESH] |Severity of Illness Index[MESH]SARS-CoV-2 infections and COVID-19 mortalities strongly correlate with(epmc).pdf DeepDyve Pubget Overpricing