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10.1080/10408347.2020.1781592

http://scihub22266oqcxt.onion/10.1080/10408347.2020.1781592
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32628049!ä!32628049

suck abstract from ncbi


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pmid32628049      Crit+Rev+Anal+Chem 2022 ; 52 (1): 19-34
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  • Analytical Methods on Determination in Pharmaceuticals and Biological Materials of Chloroquine as Available for the Treatment of COVID-19 #MMPMID32628049
  • Saka C
  • Crit Rev Anal Chem 2022[]; 52 (1): 19-34 PMID32628049show ga
  • With the outbreak caused by the severe acute respiratory syndrome coronavirus (COVID-19), people's health and existing economies on a global scale are seriously threatened. Currently, most of the countries all over the world are studying extensively to better understand the antimalarial chloroquine (CQ) and hydroxychloroquine (HCQ) for therapeutic purposes due to the COVID-19 outbreak. However, CQ and HCQ can have serious side effects, from psychiatric effects to sudden death. Therefore, a faster and more effective detection method is needed to monitor drug concentrations. In this review, a large study was conducted on the detection techniques and quantitative determination methods of CQ and its related metabolites. In this review, chromatography, electrophoresis, electroanalytical, spectroscopic, and immunological methods for CQ and related metabolites are discussed extensively. It is hoped that a better understanding of the CQ used for therapeutic purposes in the COVID-19 outbreak will be provided.
  • |*COVID-19 Drug Treatment[MESH]
  • |*Pharmaceutical Preparations[MESH]
  • |Antiviral Agents[MESH]
  • |Chloroquine[MESH]
  • |Humans[MESH]


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