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10.1016/j.jaad.2020.06.1016

http://scihub22266oqcxt.onion/10.1016/j.jaad.2020.06.1016
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32622888!7331510!32622888
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suck abstract from ncbi


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pmid32622888      J+Am+Acad+Dermatol 2020 ; 83 (4): 1118-1129
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  • The spectrum of COVID-19-associated dermatologic manifestations: An international registry of 716 patients from 31 countries #MMPMID32622888
  • Freeman EE; McMahon DE; Lipoff JB; Rosenbach M; Kovarik C; Desai SR; Harp J; Takeshita J; French LE; Lim HW; Thiers BH; Hruza GJ; Fox LP
  • J Am Acad Dermatol 2020[Oct]; 83 (4): 1118-1129 PMID32622888show ga
  • BACKGROUND: Coronavirus disease 2019 (COVID-19) has associated cutaneous manifestations. OBJECTIVE: To characterize the diversity of cutaneous manifestations of COVID-19 and facilitate understanding of the underlying pathophysiology. METHODS: Case series from an international registry from the American Academy of Dermatology and International League of Dermatological Societies. RESULTS: The registry collected 716 cases of new-onset dermatologic symptoms in patients with confirmed/suspected COVID-19. Of the 171 patients in the registry with laboratory-confirmed COVID-19, the most common morphologies were morbilliform (22%), pernio-like (18%), urticarial (16%), macular erythema (13%), vesicular (11%), papulosquamous (9.9%), and retiform purpura (6.4%). Pernio-like lesions were common in patients with mild disease, whereas retiform purpura presented exclusively in ill, hospitalized patients. LIMITATIONS: We cannot estimate incidence or prevalence. Confirmation bias is possible. CONCLUSIONS: This study highlights the array of cutaneous manifestations associated with COVID-19. Many morphologies were nonspecific, whereas others may provide insight into potential immune or inflammatory pathways in COVID-19 pathophysiology.
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Betacoronavirus/*immunology/isolation & purification[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*complications/diagnosis/immunology/virology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Incidence[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*complications/diagnosis/immunology/virology[MESH]
  • |Registries/*statistics & numerical data[MESH]
  • |SARS-CoV-2[MESH]
  • |Severity of Illness Index[MESH]
  • |Skin Diseases/diagnosis/epidemiology/*immunology/virology[MESH]


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