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10.1126/science.abc5343 http://scihub22266oqcxt.onion/10.1126/science.abc5343 32616673!7402625!32616673     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32616673&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Science 2020 ; 369 (6505): 818-823 Nephropedia Template TP {{tp|p=32616673|t=2020. Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques |pdf=|usr=}}{{32616673}} gab.com Text Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques JO: Science http://www.kidney.de/pget.php?&tw=1&pmid=32616673 #FOAvip Coronavirus disease 2019 (COVID-19), which is caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic. It is unclear whether convalescing patients have a risk of reinfection. We generated a rhesus macaque model of SARS-CoV-2 infection that was characterized by interstitial pneumonia and systemic viral dissemination mainly in the respiratory and gastrointestinal tracts. Rhesus macaques reinfected with the identical SARS-CoV-2 strain during the early recovery phase of the initial SARS-CoV-2 infection did not show detectable viral dissemination, clinical manifestations of viral disease, or histopathological changes. Comparing the humoral and cellular immunity between primary infection and rechallenge revealed notably enhanced neutralizing antibody and immune responses. Our results suggest that primary SARS-CoV-2 exposure protects against subsequent reinfection in rhesus macaques. Twit Text FOAVip Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques ????Science http://www.kidney.de/pget.php?&tw=1&pmid=32616673 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32616673 #FOAvip English Wikipedia <ref>{{Cite pmid|32616673}}</ref> Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques #MMPMID32616673 Deng W; Bao L; Liu J; Xiao C; Liu J; Xue J; Lv Q; Qi F; Gao H; Yu P; Xu Y; Qu Y; Li F; Xiang Z; Yu H; Gong S; Liu M; Wang G; Wang S; Song Z; Liu Y; Zhao W; Han Y; Zhao L; Liu X; Wei Q; Qin C Science 2020[Aug]; 369 (6505): 818-823 PMID32616673show ga Coronavirus disease 2019 (COVID-19), which is caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic. It is unclear whether convalescing patients have a risk of reinfection. We generated a rhesus macaque model of SARS-CoV-2 infection that was characterized by interstitial pneumonia and systemic viral dissemination mainly in the respiratory and gastrointestinal tracts. Rhesus macaques reinfected with the identical SARS-CoV-2 strain during the early recovery phase of the initial SARS-CoV-2 infection did not show detectable viral dissemination, clinical manifestations of viral disease, or histopathological changes. Comparing the humoral and cellular immunity between primary infection and rechallenge revealed notably enhanced neutralizing antibody and immune responses. Our results suggest that primary SARS-CoV-2 exposure protects against subsequent reinfection in rhesus macaques. |*Betacoronavirus/immunology/isolation & purification/physiology[MESH] |Anal Canal/virology[MESH] |Animals[MESH] |Antibodies, Neutralizing/blood[MESH] |Antibodies, Viral/blood[MESH] |B-Lymphocyte Subsets/immunology[MESH] |COVID-19[MESH] |Coronavirus Infections/*immunology/pathology/physiopathology/*virology[MESH] |Disease Models, Animal[MESH] |Host Microbial Interactions[MESH] |Immunity, Cellular[MESH] |Immunity, Humoral[MESH] |Lung Diseases, Interstitial/immunology/pathology/virology[MESH] |Lung/diagnostic imaging/immunology/pathology/virology[MESH] |Macaca mulatta[MESH] |Nasopharynx/virology[MESH] |Pandemics[MESH] |Pneumonia, Viral/*immunology/pathology/physiopathology/*virology[MESH] |Recurrence[MESH] |SARS-CoV-2[MESH] |T-Lymphocyte Subsets/immunology[MESH] |Viral Load[MESH]Primary exposure to SARS-CoV-2 protects against reinfection in rhesus (epmc).pdf DeepDyve Pubget Overpricing