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10.1148/radiol.2020202352 http://scihub22266oqcxt.onion/10.1148/radiol.2020202352 32614258!7336751!32614258     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32614258&cmd=llinks): Failed to open stream: HTTP request failed! 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Increased Incidence of Barotrauma in Patients with COVID-19 on Invasive Mechanical Ventilation |pdf=|usr=}}{{32614258}} gab.com Text Increased Incidence of Barotrauma in Patients with COVID-19 on Invasive Mechanical Ventilation JO: Radiology http://www.kidney.de/pget.php?&tw=1&pmid=32614258 #FOAvip Background A high number of patients with coronavirus disease 2019 (COVID-19) pneumonia who had barotrauma related to invasive mechanical ventilation at the authors' institution were observed. Purpose To determine if the rate of barotrauma in patients with COVID-19 infection was greater than in other patients requiring invasive mechanical ventilation at the authors' institution. Materials and Methods In this retrospective study, clinical and imaging data of patients seen between March 1, 2020, and April 6, 2020, who tested positive for COVID-19 and experienced barotrauma associated with invasive mechanical ventilation, were compared with patients without COVID-19 infection during the same period. Historical comparison was made to barotrauma rates of patients with acute respiratory distress syndrome from February 1, 2016, to February 1, 2020, at the authors' institution. Comparison of patient groups was performed using categoric or continuous statistical testing as appropriate, with multivariable regression analysis. Patient survival was assessed using Kaplan-Meier curves analysis. Results A total of 601 patients with COVID-19 infection underwent invasive mechanical ventilation (mean age, 63 years +/- 15 [standard deviation]; 71% men). Of the total, there were 89 (15%) patients with one or more barotrauma events for a total of 145 barotrauma events (24% overall events) (95% confidence interval [CI]: 21%, 28%). During the same period, 196 patients without COVID-19 infection (mean age, 64 years +/- 19; 52% men) with invasive mechanical ventilation had one barotrauma event (0.5%; 95% CI: 0%, 3%; P < .001 vs the group with COVID-19 infection). Of 285 patients with acute respiratory distress syndrome on invasive mechanical ventilation during the previous 4 years (mean age, 68 years +/- 17; 60% men), 28 patients (10%) had 31 barotrauma events, with an overall barotrauma rate of 11% (95% CI: 8%, 15%; P < .001 vs the group with COVID-19 infection). Barotrauma is an independent risk factor for death in COVID-19 (odds ratio = 2.2; P = .03) and is associated with a longer hospital stay (odds ratio = 0.92; P < .001). Conclusion Patients with coronavirus disease 2019 (COVID-19) infection and invasive mechanical ventilation had a higher rate of barotrauma than patients with acute respiratory distress syndrome and patients without COVID-19 infection. (c) RSNA, 2020 Online supplemental material is available for this article. Twit Text FOAVip Increased Incidence of Barotrauma in Patients with COVID-19 on Invasive Mechanical Ventilation ????Radiology http://www.kidney.de/pget.php?&tw=1&pmid=32614258 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32614258 #FOAvip English Wikipedia <ref>{{Cite pmid|32614258}}</ref> Increased Incidence of Barotrauma in Patients with COVID-19 on Invasive Mechanical Ventilation #MMPMID32614258 McGuinness G; Zhan C; Rosenberg N; Azour L; Wickstrom M; Mason DM; Thomas KM; Moore WH Radiology 2020[Nov]; 297 (2): E252-E262 PMID32614258show ga Background A high number of patients with coronavirus disease 2019 (COVID-19) pneumonia who had barotrauma related to invasive mechanical ventilation at the authors' institution were observed. Purpose To determine if the rate of barotrauma in patients with COVID-19 infection was greater than in other patients requiring invasive mechanical ventilation at the authors' institution. Materials and Methods In this retrospective study, clinical and imaging data of patients seen between March 1, 2020, and April 6, 2020, who tested positive for COVID-19 and experienced barotrauma associated with invasive mechanical ventilation, were compared with patients without COVID-19 infection during the same period. Historical comparison was made to barotrauma rates of patients with acute respiratory distress syndrome from February 1, 2016, to February 1, 2020, at the authors' institution. Comparison of patient groups was performed using categoric or continuous statistical testing as appropriate, with multivariable regression analysis. Patient survival was assessed using Kaplan-Meier curves analysis. Results A total of 601 patients with COVID-19 infection underwent invasive mechanical ventilation (mean age, 63 years +/- 15 [standard deviation]; 71% men). Of the total, there were 89 (15%) patients with one or more barotrauma events for a total of 145 barotrauma events (24% overall events) (95% confidence interval [CI]: 21%, 28%). During the same period, 196 patients without COVID-19 infection (mean age, 64 years +/- 19; 52% men) with invasive mechanical ventilation had one barotrauma event (0.5%; 95% CI: 0%, 3%; P < .001 vs the group with COVID-19 infection). Of 285 patients with acute respiratory distress syndrome on invasive mechanical ventilation during the previous 4 years (mean age, 68 years +/- 17; 60% men), 28 patients (10%) had 31 barotrauma events, with an overall barotrauma rate of 11% (95% CI: 8%, 15%; P < .001 vs the group with COVID-19 infection). Barotrauma is an independent risk factor for death in COVID-19 (odds ratio = 2.2; P = .03) and is associated with a longer hospital stay (odds ratio = 0.92; P < .001). Conclusion Patients with coronavirus disease 2019 (COVID-19) infection and invasive mechanical ventilation had a higher rate of barotrauma than patients with acute respiratory distress syndrome and patients without COVID-19 infection. (c) RSNA, 2020 Online supplemental material is available for this article. |*Betacoronavirus[MESH] |Aged[MESH] |Barotrauma/*epidemiology[MESH] |COVID-19[MESH] |Causality[MESH] |Comorbidity[MESH] |Coronavirus Infections/*epidemiology/*therapy[MESH] |Female[MESH] |Humans[MESH] |Incidence[MESH] |Male[MESH] |Middle Aged[MESH] |New York/epidemiology[MESH] |Pandemics[MESH] |Pneumonia, Viral/*epidemiology/*therapy[MESH] |Respiration, Artificial/adverse effects/*methods/*statistics & numerical data[MESH] |Retrospective Studies[MESH]Increased Incidence of Barotrauma in Patients with COVID-19 on Invasiv(epmc).pdf DeepDyve Pubget Overpricing