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10.3949/ccjm.87a.ccc037 http://scihub22266oqcxt.onion/10.3949/ccjm.87a.ccc037 32606050!ä!32606050 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cleve+Clin+J+Med 2020 ; ä (ä): ä Nephropedia Template TP {{tp|p=32606050|t=2020. COVID-19 treatment: Combining anti-inflammatory and antiviral therapeutics using a network-based approach |pdf=|usr=}}{{32606050}} gab.com Text COVID-19 treatment: Combining anti-inflammatory and antiviral therapeutics using a network-based approach JO: Cleve Clin J Med http://www.kidney.de/pget.php?&tw=1&pmid=32606050 #FOAvip To date, there are no effective antiviral medications for COVID-19. Drug repurposing, a strategy that uses existing drugs, offers potential prevention and treatment options for COVID-19. We discuss one treatment strategy that combines anti-inflammatory (melatonin) and antiviral (toremifene) agents for patients infected with SARS-CoV-2 from network medicine-based findings. We also describe the pathobiology and immunologic characteristics of COVID-19 and highlight the rationale of combination drug treatment to rescue the pulmonary and cardiovascular conditions resulting from COVID-19. A preliminary analysis reveals a high potential for the synergistic effects of melatonin and toremifene to reduce viral infection and replication, and the aberrant host inflammatory responses, offering strong biologic plausibility as an effective therapy for COVID-19. Twit Text FOAVip COVID-19 treatment: Combining anti-inflammatory and antiviral therapeutics using a network-based approach ????Cleve Clin J Med http://www.kidney.de/pget.php?&tw=1&pmid=32606050 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32606050 #FOAvip English Wikipedia <ref>{{Cite pmid|32606050}}</ref> COVID-19 treatment: Combining anti-inflammatory and antiviral therapeutics using a network-based approach #MMPMID32606050 Cheng F; Rao S; Mehra R Cleve Clin J Med 2020[Jun]; ä (ä): ä PMID32606050show ga To date, there are no effective antiviral medications for COVID-19. Drug repurposing, a strategy that uses existing drugs, offers potential prevention and treatment options for COVID-19. We discuss one treatment strategy that combines anti-inflammatory (melatonin) and antiviral (toremifene) agents for patients infected with SARS-CoV-2 from network medicine-based findings. We also describe the pathobiology and immunologic characteristics of COVID-19 and highlight the rationale of combination drug treatment to rescue the pulmonary and cardiovascular conditions resulting from COVID-19. A preliminary analysis reveals a high potential for the synergistic effects of melatonin and toremifene to reduce viral infection and replication, and the aberrant host inflammatory responses, offering strong biologic plausibility as an effective therapy for COVID-19. äCOVID-19 treatment: Combining anti-inflammatory and antiviral therapeu(epmc).pdf DeepDyve Pubget Overpricing