Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.3390/v12070699 http://scihub22266oqcxt.onion/10.3390/v12070699 32605306!7411974!32605306     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Viruses 2020 ; 12 (7): ä Nephropedia Template TP {{tp|p=32605306|t=2020. Saxifraga spinulosa-Derived Components Rapidly Inactivate Multiple Viruses Including SARS-CoV-2 |pdf=|usr=}}{{32605306}} gab.com Text Saxifraga spinulosa-Derived Components Rapidly Inactivate Multiple Viruses Including SARS-CoV-2 JO: Viruses http://www.kidney.de/pget.php?&tw=1&pmid=32605306 #FOAvip Novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza A virus (IAV), and norovirus (NV) are highly contagious pathogens that threaten human health. Here we focused on the antiviral potential of the medicinal herb, Saxifraga spinulosa (SS). Water-soluble extracts of SS were prepared, and their virus-inactivating activity was evaluated against the human virus pathogens SARS-CoV-2 and IAV; we also examined virucidal activity against feline calicivirus and murine norovirus, which are surrogates for human NV. Among our findings, we found that SS-derived gallocatechin gallate compounds were capable of inactivating all viruses tested. Interestingly, a pyrogallol-enriched fraction (Fr 1C) inactivated all viruses more rapidly and effectively than did any of the component compounds used alone. We found that 25 microg/mL of Fr 1C inactivated >99.6% of SARS-CoV-2 within 10 s (reduction of >/=2.33 log(10) TCID(50)/mL). Fr 1C resulted in the disruption of viral genomes and proteins as determined by gel electrophoresis, electron microscopy, and reverse transcription-PCR. Taken together, our results reveal the potential of Fr 1C for development as a novel antiviral disinfectant. Twit Text FOAVip Saxifraga spinulosa-Derived Components Rapidly Inactivate Multiple Viruses Including SARS-CoV-2 ????Viruses http://www.kidney.de/pget.php?&tw=1&pmid=32605306 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32605306 #FOAvip English Wikipedia <ref>{{Cite pmid|32605306}}</ref> Saxifraga spinulosa-Derived Components Rapidly Inactivate Multiple Viruses Including SARS-CoV-2 #MMPMID32605306 Takeda Y; Murata T; Jamsransuren D; Suganuma K; Kazami Y; Batkhuu J; Badral D; Ogawa H Viruses 2020[Jun]; 12 (7): ä PMID32605306show ga Novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza A virus (IAV), and norovirus (NV) are highly contagious pathogens that threaten human health. Here we focused on the antiviral potential of the medicinal herb, Saxifraga spinulosa (SS). Water-soluble extracts of SS were prepared, and their virus-inactivating activity was evaluated against the human virus pathogens SARS-CoV-2 and IAV; we also examined virucidal activity against feline calicivirus and murine norovirus, which are surrogates for human NV. Among our findings, we found that SS-derived gallocatechin gallate compounds were capable of inactivating all viruses tested. Interestingly, a pyrogallol-enriched fraction (Fr 1C) inactivated all viruses more rapidly and effectively than did any of the component compounds used alone. We found that 25 microg/mL of Fr 1C inactivated >99.6% of SARS-CoV-2 within 10 s (reduction of >/=2.33 log(10) TCID(50)/mL). Fr 1C resulted in the disruption of viral genomes and proteins as determined by gel electrophoresis, electron microscopy, and reverse transcription-PCR. Taken together, our results reveal the potential of Fr 1C for development as a novel antiviral disinfectant. |*Plants, Medicinal[MESH] |*Saxifragaceae[MESH] |Antiviral Agents/*pharmacology[MESH] |Betacoronavirus/*drug effects/ultrastructure[MESH] |Calicivirus, Feline/drug effects[MESH] |Electrophoresis, Polyacrylamide Gel[MESH] |Genome, Viral/drug effects[MESH] |Hemagglutination Tests[MESH] |Humans[MESH] |Influenza A virus/*drug effects[MESH] |Microscopy, Electron, Transmission[MESH] |Norovirus/*drug effects[MESH] |Plant Extracts/*pharmacology[MESH] |Reverse Transcriptase Polymerase Chain Reaction[MESH] |SARS-CoV-2[MESH]Saxifraga spinulosa-Derived Components Rapidly Inactivate Multiple Vir(epmc).pdf DeepDyve Pubget Overpricing