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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Biochem+Mol+Biol+Educ 2020 ; 48 (5): 452-459 Nephropedia Template TP
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CoViD-19 epidemic follows the "kinetics" of enzymes with cooperative substrate binding #MMPMID32604468
Silverstein TP
Biochem Mol Biol Educ 2020[Sep]; 48 (5): 452-459 PMID32604468show ga
The Hill equation, which models the cooperative ligand-receptor binding equilibrium, turns out to be useful in modeling the progression of infectious disease outbreaks such as CoViD-19. The equation fits well the data for total and daily case numbers, allows tentative predictions for the half-point and end point of the epidemic, and presents a mathematical characterization of how social interventions "flatten the curve" of the disease progression.