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10.1097/QAD.0000000000002607

http://scihub22266oqcxt.onion/10.1097/QAD.0000000000002607
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32604138!7499878!32604138
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suck abstract from ncbi


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pmid32604138      AIDS 2020 ; 34 (12): 1781-1787
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  • Disproportionate burden of coronavirus disease 2019 among racial minorities and those in congregate settings among a large cohort of people with HIV #MMPMID32604138
  • Meyerowitz EA; Kim AY; Ard KL; Basgoz N; Chu JT; Hurtado RM; Lee CK; He W; Minukas T; Nelson S; Ojikutu BO; Robbins G; Sanchez S; Triant VA; Zachary K; Gandhi RT
  • AIDS 2020[Oct]; 34 (12): 1781-1787 PMID32604138show ga
  • BACKGROUND: Many people living with HIV (PLWH) have comorbidities which are risk factors for severe coronavirus disease 2019 (COVID-19) or have exposures that may lead to acquisition of severe acute respiratory distress syndrome coronavirus 2. There are few studies, however, on the demographics, comorbidities, clinical presentation, or outcomes of COVID-19 in people with HIV. OBJECTIVE: To evaluate risk factors, clinical manifestations, and outcomes in a large cohort of PLWH with COVID-19. METHODS: We systematically identified all PLWH who were diagnosed with COVID-19 at a large hospital from 3 March to 26 April 2020 during an outbreak in Massachusetts. We analyzed each of the cases to extract information including demographics, medical comorbidities, clinical presentation, and illness course after COVID-19 diagnosis. RESULTS: We describe a cohort of 36 PLWH with confirmed COVID-19 and another 11 patients with probable COVID-19. Almost 85% of PLWH with confirmed COVID-19 had a comorbidity associated with severe disease, including obesity, cardiovascular disease, or hypertension. Approximately 77% of PLWH with COVID-19 were non-Hispanic Black or Latinx whereas only 40% of the PLWH in our clinic were Black or Latinx. Nearly half of PLWH with COVID-19 had exposure to congregate settings. In addition to people with confirmed COVID-19, we identified another 11 individuals with probable COVID-19, almost all of whom had negative PCR testing. CONCLUSION: In the largest cohort to date of PLWH and confirmed COVID-19, almost all had a comorbidity associated with severe disease, highlighting the importance of non-HIV risk factors in this population. The racial disparities and frequent link to congregate settings in PLWH and COVID-19 need to be explored urgently.
  • |Adult[MESH]
  • |Aged[MESH]
  • |Betacoronavirus[MESH]
  • |Black or African American/statistics & numerical data[MESH]
  • |COVID-19[MESH]
  • |Cohort Studies[MESH]
  • |Comorbidity[MESH]
  • |Coronavirus Infections/*epidemiology/ethnology[MESH]
  • |Cost of Illness[MESH]
  • |Female[MESH]
  • |HIV Infections/*epidemiology/ethnology[MESH]
  • |Hispanic or Latino/statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Massachusetts/epidemiology[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*epidemiology/ethnology[MESH]
  • |Risk Factors[MESH]


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