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10.1093/infdis/jiaa387

http://scihub22266oqcxt.onion/10.1093/infdis/jiaa387
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32601708!7337810!32601708
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suck abstract from ncbi


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pmid32601708      J+Infect+Dis 2020 ; 222 (9): 1444-1451
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  • Definition and Risks of Cytokine Release Syndrome in 11 Critically Ill COVID-19 Patients With Pneumonia: Analysis of Disease Characteristics #MMPMID32601708
  • Wang W; Liu X; Wu S; Chen S; Li Y; Nong L; Lie P; Huang L; Cheng L; Lin Y; He J
  • J Infect Dis 2020[Oct]; 222 (9): 1444-1451 PMID32601708show ga
  • Corona virus disease 2019 (COVID-19) patients with severe immune abnormalities are at risk of cytokine release syndrome (CRS). The definition, prevention, and treatment of symptoms of CRS in critically ill patients with COVID-19 are important problems. We report a single-center case series of 11 COVID-19 patients with acute respiratory distress syndrome from The First Affiliated Hospital of Guangzhou Medical University in China from 26 January 2020 to 18 February 2020. The termination date of follow-up was 19 February 2020. Eight patients were determined to have characteristics of CRS, including pulmonary inflammation, fever, and dysfunction of nonpulmonary organs. An increase in interleukin-6 in peripheral blood was the highest risk factor and an early indicator of CRS in COVID-19.
  • |*Leukocytes, Mononuclear[MESH]
  • |Aged[MESH]
  • |Betacoronavirus[MESH]
  • |Biomarkers/blood[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/blood/complications/*immunology[MESH]
  • |Critical Illness[MESH]
  • |Cytokine Release Syndrome/*blood/immunology/virology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Interleukin-6/*blood[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*blood/complications/immunology/virology[MESH]
  • |Prognosis[MESH]
  • |Risk Factors[MESH]


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