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10.1016/j.jhin.2020.06.030

http://scihub22266oqcxt.onion/10.1016/j.jhin.2020.06.030
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suck abstract from ncbi


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pmid32599011      J+Hosp+Infect 2020 ; 105 (4): 608-614
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  • Autoclave sterilization and ethanol treatment of re-used surgical masks and N95 respirators during COVID-19: impact on their performance and integrity #MMPMID32599011
  • Grinshpun SA; Yermakov M; Khodoun M
  • J Hosp Infect 2020[Aug]; 105 (4): 608-614 PMID32599011show ga
  • BACKGROUND: An exceptionally high demand for surgical masks and N95 filtering facepiece respirators (FFRs) during the COVID-19 pandemic has considerably exceeded their supply. These disposable devices are generally not approved for routine decontamination and re-use as a standard of care, while this practice has widely occurred in hospitals. The US Centers for Disease Control and Prevention allowed it "as a crisis capacity strategy". However, limited testing was conducted on the impact of specific decontamination methods on the performance of N95 FFRs and no data was presented for surgical masks. AIM: We evaluated common surgical masks and N95 respirators with respect to the changes in their performance and integrity resulting from autoclave sterilization and a 70% ethanol treatment; these methods are frequently utilized for re-used filtering facepieces in hospitals. METHODS: The filter collection efficiency and pressure drop were determined for unused masks and N95 FFRs, and for those subjected to the treatments in a variety of ways. The collection efficiency was measured for particles of approximately 0.037-3.2 mum to represent aerosolized single viruses, their agglomerates, bacteria and larger particle carriers. FINDINGS: The initial collection efficiency and the filter breathability may be compromised by sterilization in an autoclave and ethanol treatment. The effect depends on a protective device, particle size, breathing flow rate, type of treatment and other factors. Additionally, physical damages were observed in N95 respirators after autoclaving. CONCLUSION: Strategies advocating decontamination and re-use of filtering facepieces in hospitals should be re-assessed considering the data obtained in this study.
  • |*Ethanol[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*prevention & control[MESH]
  • |Guidelines as Topic[MESH]
  • |Humans[MESH]
  • |Masks/*standards[MESH]
  • |Occupational Exposure/*prevention & control[MESH]
  • |Pandemics/*prevention & control[MESH]
  • |Pneumonia, Viral/*prevention & control[MESH]
  • |Respiratory Protective Devices/*standards[MESH]
  • |SARS-CoV-2[MESH]
  • |Sterilization/*standards[MESH]
  • |United States[MESH]


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