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10.1159/000509107

http://scihub22266oqcxt.onion/10.1159/000509107
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suck abstract from ncbi


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pmid32594085      Blood+Purif 2021 ; 50 (2): 257-260
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  • Early Hemoperfusion for Cytokine Removal May Contribute to Prevention of Intubation in Patients Infected with COVID-19 #MMPMID32594085
  • Esmaeili Vardanjani A; Ronco C; Rafiei H; Golitaleb M; Pishvaei MH; Mohammadi M
  • Blood Purif 2021[]; 50 (2): 257-260 PMID32594085show ga
  • Hemoperfusion (HP) was helpful to prevent the development and progression of acute respiratory distress syndrome (ARDS), acute kidney injury (AKI), liver failure, and septic shock by removing cytokines and other inflammatory mediators and ultimately preventing progression toward multiple organ failure. A 54-year-old man diagnosed with COVID-19 was hospitalized in the intensive care unit. The patient's O2 saturation was 80% using an oxygen mask, which was gradually declining. After 4 sessions of HP/continuous renal replacement therapies (CRRT), O2 saturation reached to 95%, and the patient was transferred to the general ward. Performing HP/CRRT at the early stages of ARDS can obviate the need for intubating patients with COVID-19. Punctual and early use of HP and CRRT in the treatment of ARDS in patients with COVID-19 prevented the progression of ARDS and patient intubation, reduced respiratory distress and the patient's dependence on oxygen, prevented other complications such as AKI and septic shock in the patient, and reduced mortality and hospital length of stay.
  • |*Continuous Renal Replacement Therapy[MESH]
  • |*Hemoperfusion[MESH]
  • |*Intubation, Intratracheal[MESH]
  • |*SARS-CoV-2[MESH]
  • |Acute Kidney Injury/etiology/prevention & control[MESH]
  • |Anti-Bacterial Agents/therapeutic use[MESH]
  • |Anticoagulants/therapeutic use[MESH]
  • |Antiviral Agents/therapeutic use[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |COVID-19/blood/complications/*therapy[MESH]
  • |Critical Care/methods[MESH]
  • |Cytokine Release Syndrome/blood/etiology/*therapy[MESH]
  • |Cytokines/*blood[MESH]
  • |Diabetes Mellitus, Type 2/complications/drug therapy[MESH]
  • |Humans[MESH]
  • |Hypertension/complications/drug therapy[MESH]
  • |Inflammation/blood/etiology[MESH]
  • |Length of Stay/statistics & numerical data[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Oxygen/blood[MESH]
  • |Respiratory Distress Syndrome/blood/etiology/prevention & control/*therapy[MESH]


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