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10.1097/MD.0000000000020837

http://scihub22266oqcxt.onion/10.1097/MD.0000000000020837
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32590775!7328934!32590775
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suck abstract from ncbi


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pmid32590775      Medicine+(Baltimore) 2020 ; 99 (26): e20837
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  • Chest CT of COVID-19 in patients with a negative first RT-PCR test: Comparison with patients with a positive first RT-PCR test #MMPMID32590775
  • Chen ZH; Li YJ; Wang XJ; Ye YF; Wu BL; Zhang Y; Xuan WL; Bao JF; Deng XY
  • Medicine (Baltimore) 2020[Jun]; 99 (26): e20837 PMID32590775show ga
  • To compare clinical and imaging features between patients with an initial negative reverse-transcription-polymerase chain-reaction (RT-PCR) test and patients with an initial positive RT-PCR test. CT follow-up analysis in the negative RT-PCR group is also described.Thirty-three patients with SARS-CoV-2 infection confirmed by RT-PCR, with 216 lesions upon CT, were included. Demographic information and chest CT imaging features were collected.The average age in the whole study group was 46.9 +/- 11.1 years, with 18 males and 15 females. Patients in the positive RT-PCR test group were more likely to have a fever than patients in the negative RT-PCR test group (85.7% vs 50%, P < .05). Lesions in the positive group were more likely to be located in the peripheral area than lesions in the negative group (83.6% vs 68.2%, P < .05). Regarding the appearance of 216 lesions, ground-glass opacities (GGOs) with consolidation (43.2%) was the most common appearance in the negative group, followed by pure GGOs (31.8%), while in the positive group, pure GGOs (32%) and GGOs with interlobular septal thickening (32.8%) were both most frequent, and the difference between them was evident (P < .05). For the follow-up analysis, the largest short-axis of a lesion was smaller upon follow-up (median size 13.6 mm vs 14 mm), albeit by a smaller margin. Pure GGOs decreased in frequency, from 31.3% to 21.3%, while consolidation increased in frequency, from 7.5% to 12.5%.The manifestations of COVID-19 in patients with a first negative RT-PCR test and patients with a positive first RT-PCR test are different to some extent. The consolidation component may increase after follow-up.
  • |*Clinical Laboratory Techniques[MESH]
  • |*Real-Time Polymerase Chain Reaction[MESH]
  • |*Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |Adult[MESH]
  • |Betacoronavirus/*isolation & purification[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |COVID-19 Vaccines[MESH]
  • |Coronavirus Infections/diagnosis/*diagnostic imaging[MESH]
  • |False Negative Reactions[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/diagnosis/*diagnostic imaging[MESH]
  • |Radiography, Thoracic/*statistics & numerical data[MESH]
  • |Retrospective Studies[MESH]


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