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10.1016/j.micinf.2020.06.006

http://scihub22266oqcxt.onion/10.1016/j.micinf.2020.06.006
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32590062!7311339!32590062
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suck abstract from ncbi


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pmid32590062      Microbes+Infect 2020 ; 22 (9): 405-406
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  • Out of the frying pan and into the fire? Due diligence warranted for ADE in COVID-19 #MMPMID32590062
  • Coish JM; MacNeil AJ
  • Microbes Infect 2020[Oct]; 22 (9): 405-406 PMID32590062show ga
  • Antibody-dependent enhancement (ADE) is an atypical immunological paradox commonly associated with dengue virus re-infection. However, various research models have demonstrated this phenomenon with other viral families, including Coronaviridae. Recently, ADE in SARS-CoV-2 has emerged as one hypothesis to explain severe clinical manifestations. Whether SARS-CoV-2 is augmented by ADE remains undetermined and has therefore garnered criticism for the improper attribution of the phenomenon to the pandemic. Thus, critical evaluation of ADE in SARS-CoV-2 vaccine development will be indispensable to avoid a global setback and the erosion of public trust.
  • |*Antibody-Dependent Enhancement[MESH]
  • |*Pandemics/prevention & control[MESH]
  • |Antibodies, Neutralizing/*biosynthesis[MESH]
  • |Antibodies, Viral/*biosynthesis[MESH]
  • |Betacoronavirus/immunology/*pathogenicity[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Vaccines[MESH]
  • |Coronavirus Infections/*epidemiology/immunology/prevention & control/psychology[MESH]
  • |Humans[MESH]
  • |Patient Safety[MESH]
  • |Pneumonia, Viral/*epidemiology/immunology/prevention & control/psychology[MESH]
  • |SARS-CoV-2[MESH]
  • |Severity of Illness Index[MESH]
  • |Vaccination Refusal/psychology[MESH]
  • |Vaccination/adverse effects/psychology[MESH]
  • |Viral Vaccines/*administration & dosage/adverse effects[MESH]


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