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10.3892/ijmm.2020.4659 http://scihub22266oqcxt.onion/10.3892/ijmm.2020.4659 32588061!7388827!32588061     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Mol+Med 2020 ; 46 (3): 903-912 Nephropedia Template TP {{tp|p=32588061|t=2020. Entangling COVID-19 associated thrombosis into a secondary antiphospholipid antibody syndrome: Diagnostic and therapeutic perspectives (Review) |pdf=|usr=}}{{32588061}} gab.com Text Entangling COVID-19 associated thrombosis into a secondary antiphospholipid antibody syndrome: Diagnostic and therapeutic perspectives (Review) JO: Int J Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=32588061 #FOAvip The severe acute respiratory syndrome coronavirus 2 (SARS?CoV?2) is a novel beta coronavirus that is the etiological agent of the pandemic coronavirus disease 2019 (COVID?19) that at the time of writing (June 16, 2020) has infected almost 6 million people with some 450,000 deaths. These numbers are still rising daily. Most (some 80%) cases of COVID?19 infection are asymptomatic, a substantial number of cases (15%) require hospitalization and an additional fraction of patients (5%) need recovery in intensive care units. Mortality for COVID?19 infection appears to occur globally between 0.1 and 0.5% of infected patients although the frequency of lethality is significantly augmented in the elderly and in patients with other comorbidities. The development of acute respiratory distress syndrome and episodes of thromboembolism that may lead to disseminated intravascular coagulation (DIC) represent the primary causes of lethality during COVID?19 infection. Increasing evidence suggests that thrombotic diathesis is due to multiple derangements of the coagulation system including marked elevation of D?dimer that correlate negatively with survival. We propose here that the thromboembolic events and eventually the development of DIC provoked by SARS?CoV?2 infection may represent a secondary anti?phospholipid antibody syndrome (APS). We will apply both Baconian inductivism and Cartesian deductivism to prove that secondary APS is likely responsible for coagulopathy during the course of COVID?19 infection. Diagnostic and therapeutic implications of this are also discussed. Twit Text FOAVip Entangling COVID-19 associated thrombosis into a secondary antiphospholipid antibody syndrome: Diagnostic and therapeutic perspectives (Review) ????Int J Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=32588061 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32588061 #FOAvip English Wikipedia <ref>{{Cite pmid|32588061}}</ref> Entangling COVID-19 associated thrombosis into a secondary antiphospholipid antibody syndrome: Diagnostic and therapeutic perspectives (Review) #MMPMID32588061 Cavalli E; Bramanti A; Ciurleo R; Tchorbanov AI; Giordano A; Fagone P; Belizna C; Bramanti P; Shoenfeld Y; Nicoletti F Int J Mol Med 2020[Sep]; 46 (3): 903-912 PMID32588061show ga The severe acute respiratory syndrome coronavirus 2 (SARS?CoV?2) is a novel beta coronavirus that is the etiological agent of the pandemic coronavirus disease 2019 (COVID?19) that at the time of writing (June 16, 2020) has infected almost 6 million people with some 450,000 deaths. These numbers are still rising daily. Most (some 80%) cases of COVID?19 infection are asymptomatic, a substantial number of cases (15%) require hospitalization and an additional fraction of patients (5%) need recovery in intensive care units. Mortality for COVID?19 infection appears to occur globally between 0.1 and 0.5% of infected patients although the frequency of lethality is significantly augmented in the elderly and in patients with other comorbidities. The development of acute respiratory distress syndrome and episodes of thromboembolism that may lead to disseminated intravascular coagulation (DIC) represent the primary causes of lethality during COVID?19 infection. Increasing evidence suggests that thrombotic diathesis is due to multiple derangements of the coagulation system including marked elevation of D?dimer that correlate negatively with survival. We propose here that the thromboembolic events and eventually the development of DIC provoked by SARS?CoV?2 infection may represent a secondary anti?phospholipid antibody syndrome (APS). We will apply both Baconian inductivism and Cartesian deductivism to prove that secondary APS is likely responsible for coagulopathy during the course of COVID?19 infection. Diagnostic and therapeutic implications of this are also discussed. |Antiphospholipid Syndrome/immunology/*pathology[MESH] |Antiviral Agents/therapeutic use[MESH] |Betacoronavirus[MESH] |Blood Coagulation/physiology[MESH] |COVID-19[MESH] |Coronavirus Infections/drug therapy/immunology/*pathology[MESH] |Disseminated Intravascular Coagulation/immunology/*pathology[MESH] |Fibrin Fibrinogen Degradation Products/metabolism[MESH] |Humans[MESH] |Pandemics[MESH] |Phospholipids/immunology[MESH] |Pneumonia, Viral/drug therapy/immunology/*pathology[MESH] |SARS-CoV-2[MESH] |Thromboembolism/immunology/*pathology[MESH]Entangling COVID-19 associated thrombosis into a secondary antiphospho(epmc).pdf DeepDyve Pubget Overpricing