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10.1002/jmv.26224

http://scihub22266oqcxt.onion/10.1002/jmv.26224
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32584487!7361761!32584487
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suck abstract from ncbi


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pmid32584487      J+Med+Virol 2021 ; 93 (1): 424-433
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  • Multisystem inflammatory syndrome in children related to COVID-19: A New York City experience #MMPMID32584487
  • Riollano-Cruz M; Akkoyun E; Briceno-Brito E; Kowalsky S; Reed J; Posada R; Sordillo EM; Tosi M; Trachtman R; Paniz-Mondolfi A
  • J Med Virol 2021[Jan]; 93 (1): 424-433 PMID32584487show ga
  • In December 2019, the 2019, a novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) first emerged in Wuhan, China. This has now spread worldwide and was declared a pandemic by March 2020. Initially, the pediatric population was described as a low risk for severe COVID-19. However, reports have emerged recently of cases of COVID-19 in children with a systemic inflammatory disease, with features that overlap with Kawasaki disease (KD). We describe the first 15 cases with the multi-systeminflammatory syndrome in children (MIS-C), temporally related to COVID-19, who presented for care to a tertiary pediatric referral center in New York City. We discuss the disproportionate burden of disease among Hispanic/Latino and Black/African American ancestry, the distinct cytokine signature across the disease spectrum (IL-1/IL-6), and the potential role and pathogenesis of SARS-CoV-2 in this new clinical entity.
  • |Adolescent[MESH]
  • |COVID-19/*complications/epidemiology/immunology[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Cytokines/*immunology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |New York City/epidemiology[MESH]
  • |Retrospective Studies[MESH]
  • |Systemic Inflammatory Response Syndrome/*epidemiology[MESH]
  • |Tertiary Care Centers[MESH]


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