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10.24875/RIC.20000237 http://scihub22266oqcxt.onion/10.24875/RIC.20000237 32584322!ä!32584322 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Rev+Invest+Clin 2020 ; 72 (3): 159-164 Nephropedia Template TP {{tp|p=32584322|t=2020. INFUSION OF CONVALESCENT PLASMA IS ASSOCIATED WITH CLINICAL IMPROVEMENT IN CRITICALLY ILL PATIENTS WITH COVID-19: A PILOT STUDY |pdf=|usr=}}{{32584322}} gab.com Text INFUSION OF CONVALESCENT PLASMA IS ASSOCIATED WITH CLINICAL IMPROVEMENT IN CRITICALLY ILL PATIENTS WITH COVID-19: A PILOT STUDY JO: Rev Invest Clin http://www.kidney.de/pget.php?&tw=1&pmid=32584322 #FOAvip BACKGROUND: The ideal treatment of coronavirus disease (COVID)-19 has yet to be defined, but convalescent plasma (CoPla) has been successfully employed. OBJECTIVE: The objective of the study was to study the safety and outcomes of the administration of CoPla to individuals with severe COVID-19 in an academic medical center. METHODS: Ten patients were prospectively treated with plasma from COVID-19 convalescent donors. RESULTS: Over 8 days, the sequential organ failure assessment score dropped significantly in all patients, from 3 to 1.5 (p = 0.014); the Kirby index (PaO(2)/FiO(2)) score increased from 124 to 255, (p < 0.0001), body temperature decreased significantly from 38.1 to 36.9 degrees C (p = 0.0058), and ferritin levels also dropped significantly from 1736.6 to 1061.8 ng/ml (p = 0.0001). Chest X-rays improved in 7/10 cases and in 6/10, computerized tomography scans also revealed improvement of the lung injury. Decreases in C-reactive protein and D-dimer levels were also observed. Three of five patients on mechanical ventilation support could be extubated, nine were transferred to conventional hospital floors, and six were sent home; two patients died. The administration of CoPla had no side effects and the 24-day overall survival was 77%. CONCLUSIONS: Although other treatments were also administered to the patients and as a result data are difficult to interpret, it seems that the addition of CoPla improved pulmonary function. Twit Text FOAVip INFUSION OF CONVALESCENT PLASMA IS ASSOCIATED WITH CLINICAL IMPROVEMENT IN CRITICALLY ILL PATIENTS WITH COVID-19: A PILOT STUDY ????Rev Invest Clin http://www.kidney.de/pget.php?&tw=1&pmid=32584322 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32584322 #FOAvip English Wikipedia <ref>{{Cite pmid|32584322}}</ref> INFUSION OF CONVALESCENT PLASMA IS ASSOCIATED WITH CLINICAL IMPROVEMENT IN CRITICALLY ILL PATIENTS WITH COVID-19: A PILOT STUDY #MMPMID32584322 Olivares-Gazca JC; Priesca-Marin JM; Ojeda-Laguna M; Garces-Eisele J; Soto-Olvera S; Palacios-Alonso A; Izquierdo-Vega J; Chacon-Cano R; Arizpe-Bravo D; Lopez-Trujillo MA; Cantero-Fortiz Y; Fernandez-Lara D; Ruiz-Delgado GJ; Ruiz-Arguelles GJ Rev Invest Clin 2020[]; 72 (3): 159-164 PMID32584322show ga BACKGROUND: The ideal treatment of coronavirus disease (COVID)-19 has yet to be defined, but convalescent plasma (CoPla) has been successfully employed. OBJECTIVE: The objective of the study was to study the safety and outcomes of the administration of CoPla to individuals with severe COVID-19 in an academic medical center. METHODS: Ten patients were prospectively treated with plasma from COVID-19 convalescent donors. RESULTS: Over 8 days, the sequential organ failure assessment score dropped significantly in all patients, from 3 to 1.5 (p = 0.014); the Kirby index (PaO(2)/FiO(2)) score increased from 124 to 255, (p < 0.0001), body temperature decreased significantly from 38.1 to 36.9 degrees C (p = 0.0058), and ferritin levels also dropped significantly from 1736.6 to 1061.8 ng/ml (p = 0.0001). Chest X-rays improved in 7/10 cases and in 6/10, computerized tomography scans also revealed improvement of the lung injury. Decreases in C-reactive protein and D-dimer levels were also observed. Three of five patients on mechanical ventilation support could be extubated, nine were transferred to conventional hospital floors, and six were sent home; two patients died. The administration of CoPla had no side effects and the 24-day overall survival was 77%. CONCLUSIONS: Although other treatments were also administered to the patients and as a result data are difficult to interpret, it seems that the addition of CoPla improved pulmonary function. |*Betacoronavirus/immunology/isolation & purification[MESH] |Adult[MESH] |Aged[MESH] |Antibodies, Viral/blood[MESH] |Biomarkers[MESH] |Body Temperature[MESH] |C-Reactive Protein/analysis[MESH] |COVID-19[MESH] |COVID-19 Drug Treatment[MESH] |COVID-19 Serotherapy[MESH] |Combined Modality Therapy[MESH] |Convalescence[MESH] |Coronavirus Infections/blood/diagnostic imaging/drug therapy/*therapy[MESH] |Female[MESH] |Ferritins/blood[MESH] |Humans[MESH] |Immunization, Passive[MESH] |Kaplan-Meier Estimate[MESH] |Lung/diagnostic imaging[MESH] |Male[MESH] |Middle Aged[MESH] |Pandemics[MESH] |Pilot Projects[MESH] |Plasma[MESH] |Pneumonia, Viral/blood/diagnostic imaging/drug therapy/*therapy[MESH] |Prospective Studies[MESH] |Respiration, Artificial[MESH] |SARS-CoV-2[MESH] |Severity of Illness Index[MESH] |Tomography, X-Ray Computed[MESH] |Treatment Outcome[MESH]INFUSION OF CONVALESCENT PLASMA IS ASSOCIATED WITH CLINICAL IMPROVEMEN(epmc).pdf DeepDyve Pubget Overpricing