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10.1080/07391102.2020.1780944 http://scihub22266oqcxt.onion/10.1080/07391102.2020.1780944 32583729!7332869!32583729     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Biomol+Struct+Dyn 2021 ; 39 (13): 4878-4892 Nephropedia Template TP {{tp|p=32583729|t=2021. Immunoinformatics study to search epitopes of spike glycoprotein from SARS-CoV-2 as potential vaccine |pdf=|usr=}}{{32583729}} gab.com Text Immunoinformatics study to search epitopes of spike glycoprotein from SARS-CoV-2 as potential vaccine JO: J Biomol Struct Dyn http://www.kidney.de/pget.php?&tw=1&pmid=32583729 #FOAvip The Coronavirus disease named COVID-19 is caused by the virus reported in 2019 first identified in China. The cases of this disease have increased and as of June 1(st), 2020 there are more than 216 countries affected. Pharmacological treatments have been proposed based on the resemblance of the HIV virus. With regard to prevention there is no vaccine, thus, we proposed to explore the spike protein due to its presence on the viral surface, and it also contains the putative viral entry receptor as well as the fusion peptide (important in the genome release). In this work we have employed In Silico techniques such as immunoinformatics tools which permit the identification of potential immunogenic regions on the viral surface (spike glycoprotein). From these analyses, we identified four epitopes E332-370, E627-651, E440-464 and E694-715 that accomplish essential features such as promiscuity, conservation grade, exposure and universality, and they also form stable complexes with MHCII molecule. We suggest that these epitopes could generate a specific immune response, and thus, they could be used for future applications such as the design of new epitope vaccines against the SARS-CoV-2.Communicated by Ramaswamy H. Sarma. Twit Text FOAVip Immunoinformatics study to search epitopes of spike glycoprotein from SARS-CoV-2 as potential vaccine ????J Biomol Struct Dyn http://www.kidney.de/pget.php?&tw=1&pmid=32583729 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32583729 #FOAvip English Wikipedia <ref>{{Cite pmid|32583729}}</ref> Immunoinformatics study to search epitopes of spike glycoprotein from SARS-CoV-2 as potential vaccine #MMPMID32583729 Lizbeth RG; Jazmin GM; Jose CB; Marlet MA J Biomol Struct Dyn 2021[Aug]; 39 (13): 4878-4892 PMID32583729show ga The Coronavirus disease named COVID-19 is caused by the virus reported in 2019 first identified in China. The cases of this disease have increased and as of June 1(st), 2020 there are more than 216 countries affected. Pharmacological treatments have been proposed based on the resemblance of the HIV virus. With regard to prevention there is no vaccine, thus, we proposed to explore the spike protein due to its presence on the viral surface, and it also contains the putative viral entry receptor as well as the fusion peptide (important in the genome release). In this work we have employed In Silico techniques such as immunoinformatics tools which permit the identification of potential immunogenic regions on the viral surface (spike glycoprotein). From these analyses, we identified four epitopes E332-370, E627-651, E440-464 and E694-715 that accomplish essential features such as promiscuity, conservation grade, exposure and universality, and they also form stable complexes with MHCII molecule. We suggest that these epitopes could generate a specific immune response, and thus, they could be used for future applications such as the design of new epitope vaccines against the SARS-CoV-2.Communicated by Ramaswamy H. Sarma. |*COVID-19[MESH] |COVID-19 Vaccines/*immunology[MESH] |Epitopes, B-Lymphocyte[MESH] |Epitopes, T-Lymphocyte[MESH] |Glycoproteins[MESH] |Humans[MESH] |SARS-CoV-2[MESH]Immunoinformatics study to search epitopes of spike glycoprotein from (epmc).pdf DeepDyve Pubget Overpricing