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10.1111/tid.13382 http://scihub22266oqcxt.onion/10.1111/tid.13382 32583620!7361062!32583620     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Transpl+Infect+Dis 2020 ; 22 (5): e13382 Nephropedia Template TP {{tp|p=32583620|t=2020. COVID-19 in recent heart transplant recipients: Clinicopathologic features and early outcomes |pdf=|usr=}}{{32583620}} gab.com Text COVID-19 in recent heart transplant recipients: Clinicopathologic features and early outcomes JO: Transpl Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32583620 #FOAvip BACKGROUND: The impact of COVID-19 on heart transplant (HTx) recipients remains unclear, particularly in the early post-transplant period. METHODS: We share novel insights from our experience in five HTx patients with COVID-19 (three within 2 months post-transplant) from our institution at the epicenter of the pandemic. RESULTS: All five exhibited moderate (requiring hospitalization, n = 3) or severe (requiring ICU and/or mechanical ventilation, n = 2) illness. Both cases with severe illness were transplanted approximately 6 weeks before presentation and acquired COVID-19 through community spread. All five patients were on immunosuppressive therapy with mycophenolate mofetil (MMF) and tacrolimus, and three that were transplanted within the prior 2 months were additionally on prednisone. The two cases with severe illness had profound lymphopenia with markedly elevated C-reactive protein, procalcitonin, and ferritin. All had bilateral ground-glass opacities on chest imaging. MMF was discontinued in all five, and both severe cases received convalescent plasma. All three recent transplants underwent routine endomyocardial biopsies, revealing mild (n = 1) or no acute cellular rejection (n = 2), and no visible viral particles on electron microscopy. Within 30 days of admission, the two cases with severe illness remain hospitalized but have clinically improved, while the other three have been discharged. CONCLUSIONS: COVID-19 appears to negatively impact outcomes early after heart transplantation. Twit Text FOAVip COVID-19 in recent heart transplant recipients: Clinicopathologic features and early outcomes ????Transpl Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32583620 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32583620 #FOAvip English Wikipedia <ref>{{Cite pmid|32583620}}</ref> COVID-19 in recent heart transplant recipients: Clinicopathologic features and early outcomes #MMPMID32583620 Lima B; Gibson GT; Vullaganti S; Malhame K; Maybaum S; Hussain ST; Shah S; Majure DT; Wallach F; Jang K; Bijol V; Esposito MJ; Williamson AK; Thomas RM; Bhuiya TA; Fernandez HA; Stevens GR Transpl Infect Dis 2020[Oct]; 22 (5): e13382 PMID32583620show ga BACKGROUND: The impact of COVID-19 on heart transplant (HTx) recipients remains unclear, particularly in the early post-transplant period. METHODS: We share novel insights from our experience in five HTx patients with COVID-19 (three within 2 months post-transplant) from our institution at the epicenter of the pandemic. RESULTS: All five exhibited moderate (requiring hospitalization, n = 3) or severe (requiring ICU and/or mechanical ventilation, n = 2) illness. Both cases with severe illness were transplanted approximately 6 weeks before presentation and acquired COVID-19 through community spread. All five patients were on immunosuppressive therapy with mycophenolate mofetil (MMF) and tacrolimus, and three that were transplanted within the prior 2 months were additionally on prednisone. The two cases with severe illness had profound lymphopenia with markedly elevated C-reactive protein, procalcitonin, and ferritin. All had bilateral ground-glass opacities on chest imaging. MMF was discontinued in all five, and both severe cases received convalescent plasma. All three recent transplants underwent routine endomyocardial biopsies, revealing mild (n = 1) or no acute cellular rejection (n = 2), and no visible viral particles on electron microscopy. Within 30 days of admission, the two cases with severe illness remain hospitalized but have clinically improved, while the other three have been discharged. CONCLUSIONS: COVID-19 appears to negatively impact outcomes early after heart transplantation. |Aged[MESH] |Allografts/immunology/*pathology/ultrastructure[MESH] |Biopsy[MESH] |COVID-19 Nucleic Acid Testing[MESH] |COVID-19/diagnosis/epidemiology/*immunology/pathology[MESH] |Endocardium/immunology/*pathology/ultrastructure[MESH] |Female[MESH] |Graft Rejection/immunology/*pathology/prevention & control[MESH] |Heart Transplantation/*adverse effects[MESH] |Humans[MESH] |Immunosuppressive Agents/adverse effects[MESH] |Male[MESH] |Microscopy, Electron[MESH] |Middle Aged[MESH] |Myocardium/immunology/*pathology/ultrastructure[MESH] |New York City/epidemiology[MESH] |Pandemics[MESH] |Retrospective Studies[MESH] |SARS-CoV-2/immunology/isolation & purification[MESH] |Severity of Illness Index[MESH]COVID-19 in recent heart transplant recipients: Clinicopathologic feat(epmc).pdf DeepDyve Pubget Overpricing