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Sars-CoV-2: A clinical update - II #MMPMID32578794
Cespedes MDS; Souza JCRP
Rev Assoc Med Bras (1992) 2020[Apr]; 66 (4): 547-557 PMID32578794show ga
INTRODUCTION: A covid-19 pandemic decreed by WHO has raised greater awareness of it. EPIDEMIOLOGY: The infection, reached the mark of 2,000,000 patients in 33 countries and caused the risk of the presence of comorbidities and advanced age. TRANSMISSIBILITY: The transmissibility calculated so far is similar to the H1N1 epidemic, but with lower mortality rates. PHYSIOPATHOLOGY: The SARS-CoV-2 virus, of the Coronaviridae family, has the capacity for cellular invasion through the angiotensin-converting enzyme 2 does not have a lower respiratory epithelium and in the cells of the small intestine mucosa. CLINICAL MANIFESTATIONS: a presentation can be divided into mild (fever, fatigue, cough, myalgia, and sputum) and severe (cyanosis, dyspnoea, tachypnea, chest pain, hypoxemia and need for clinical measurement) and has an estimated estimate of 2%. DIAGNOSIS: allows the detection of viral load in CRP-TR of patients with high clinical suspicion. TREATMENT: based on supportive measures and infection control. In severe cases, the use of medications such as hydroxychloroquine and azithromycin or medication can be promising. Take care to avoid the use of corticosteroids. There are no restrictions on the use of resources and IECAs / BRAs.
Rev+Assoc+Med+Bras+(1992) 2020 ; 66 (4): 547-557
