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10.1080/15548627.2020.1782022

http://scihub22266oqcxt.onion/10.1080/15548627.2020.1782022
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32578486!7751505!32578486
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suck abstract from ncbi


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pmid32578486      Autophagy 2020 ; 16 (12): 2271-2272
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  • Autophagy/virophagy: a "disposal strategy" to combat COVID-19 #MMPMID32578486
  • Mijaljica D; Klionsky DJ
  • Autophagy 2020[Dec]; 16 (12): 2271-2272 PMID32578486show ga
  • Given the devastating consequences of the current COVID-19 pandemic and its impact on all of us, the question arises as to whether manipulating the cellular degradation (recycling, waste disposal) mechanism known as macroautophagy/autophagy (in particular, the selective degradation of virus particles, termed virophagy) might be a beneficial approach to fight the novel coronavirus, SARS-CoV-2. Knowing that "autophagy can reprocess everything", it seems almost inevitable that, sooner rather than later, a further hypothesis-driven work will detail the role of virophagy as a fundamental "disposal strategy" against COVID-19, yielding most needed therapeutic interventions. Abbreviations: ATG, autophagy-related; CoV/CoVs coronavirus/coronaviruses; COVID-19, coronavirus disease 2019; MERS-CoV, Middle East respiratory syndrome coronavirus; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
  • |Autophagy/*physiology[MESH]
  • |COVID-19/epidemiology/immunology/pathology/*therapy[MESH]
  • |Coronavirus Infections/epidemiology/immunology/therapy[MESH]
  • |Disease Outbreaks[MESH]
  • |Humans[MESH]
  • |Immunity, Cellular/*physiology[MESH]
  • |Middle East Respiratory Syndrome Coronavirus/physiology[MESH]
  • |Pandemics[MESH]
  • |Phagocytosis/*physiology[MESH]
  • |SARS-CoV-2/*immunology/pathogenicity[MESH]


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