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10.1016/j.clim.2020.108516 http://scihub22266oqcxt.onion/10.1016/j.clim.2020.108516 32574709!7305921!32574709     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Immunol 2020 ; 218 (ä): 108516 Nephropedia Template TP {{tp|p=32574709|t=2020. COVID-19 pneumonia: CD8(+) T and NK cells are decreased in number but compensatory increased in cytotoxic potential |pdf=|usr=}}{{32574709}} gab.com Text COVID-19 pneumonia: CD8(+) T and NK cells are decreased in number but compensatory increased in cytotoxic potential JO: Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32574709 #FOAvip BACKGROUND: Coronavirus disease 2019 (COVID-19) is posing a huge threat to human health worldwide. We aim to investigate the immune status of CD8(+) T and NK cells in COVID-19 patients. METHODS: The count and immune status of lymphocytes were detected by flow cytometry in 32 COVID-19 patients and 18 healthy individuals. RESULTS: As the disease progression in COVID-19 patients, CD8(+) T and NK cells were significantly decreased in absolute number but highly activated. After patients' condition improved, the count and immune status of CD8(+) T and NK cells restored to some extent. GrA(+)CD8(+) T and perforin(+) NK cells had good sensitivity and specificity for assisting diagnosis of COVID-19. CONCLUSIONS: As the disease progression, the declined lymphocytes in COVID-19 patients might lead to compensatory activation of CD8(+) T and NK cells. GrA(+)CD8(+) T and perforin(+) NK cells might be used as meaningful indicators for assisting diagnosis of COVID-19. Twit Text FOAVip COVID-19 pneumonia: CD8(+) T and NK cells are decreased in number but compensatory increased in cytotoxic potential ????Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32574709 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32574709 #FOAvip English Wikipedia <ref>{{Cite pmid|32574709}}</ref> COVID-19 pneumonia: CD8(+) T and NK cells are decreased in number but compensatory increased in cytotoxic potential #MMPMID32574709 Jiang Y; Wei X; Guan J; Qin S; Wang Z; Lu H; Qian J; Wu L; Chen Y; Chen Y; Lin X Clin Immunol 2020[Sep]; 218 (ä): 108516 PMID32574709show ga BACKGROUND: Coronavirus disease 2019 (COVID-19) is posing a huge threat to human health worldwide. We aim to investigate the immune status of CD8(+) T and NK cells in COVID-19 patients. METHODS: The count and immune status of lymphocytes were detected by flow cytometry in 32 COVID-19 patients and 18 healthy individuals. RESULTS: As the disease progression in COVID-19 patients, CD8(+) T and NK cells were significantly decreased in absolute number but highly activated. After patients' condition improved, the count and immune status of CD8(+) T and NK cells restored to some extent. GrA(+)CD8(+) T and perforin(+) NK cells had good sensitivity and specificity for assisting diagnosis of COVID-19. CONCLUSIONS: As the disease progression, the declined lymphocytes in COVID-19 patients might lead to compensatory activation of CD8(+) T and NK cells. GrA(+)CD8(+) T and perforin(+) NK cells might be used as meaningful indicators for assisting diagnosis of COVID-19. |Aged[MESH] |Aged, 80 and over[MESH] |Betacoronavirus/immunology/*pathogenicity[MESH] |Biomarkers/blood[MESH] |CD4-Positive T-Lymphocytes/immunology/pathology/virology[MESH] |COVID-19[MESH] |COVID-19 Testing[MESH] |Case-Control Studies[MESH] |China[MESH] |Clinical Laboratory Techniques/methods[MESH] |Coronavirus Infections/blood/*diagnosis/immunology/pathology[MESH] |Disease Progression[MESH] |Female[MESH] |Gene Expression[MESH] |Granzymes/blood/*genetics/immunology[MESH] |Humans[MESH] |Killer Cells, Natural/*immunology/pathology/virology[MESH] |Lymphocyte Activation[MESH] |Lymphocyte Count[MESH] |Male[MESH] |Middle Aged[MESH] |Pandemics[MESH] |Perforin/blood/*genetics/immunology[MESH] |Pneumonia, Viral/blood/*diagnosis/immunology/pathology[MESH] |Prognosis[MESH] |ROC Curve[MESH] |SARS-CoV-2[MESH] |Severity of Illness Index[MESH]COVID-19 pneumonia: CD8(+) T and NK cells are decreased in number but (epmc).pdf DeepDyve Pubget Overpricing