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10.3389/fphar.2020.00796

http://scihub22266oqcxt.onion/10.3389/fphar.2020.00796
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32574237!7264370!32574237
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suck abstract from ncbi


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pmid32574237      Front+Pharmacol 2020 ; 11 (ä): 796
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  • Reducing the Fatality Rate of COVID-19 by Applying Clinical Insights From Immuno-Oncology and Lung Transplantation #MMPMID32574237
  • Uckun FM
  • Front Pharmacol 2020[]; 11 (ä): 796 PMID32574237show ga
  • There is an urgent need to identify effective strategies that can stop or reverse the inflammatory process that causes acute lung injury, ARDS, and multi-organ failure in COVID-19. Adaptive clinical trials with parallel enrollment to different arms each evaluating a rationally designed combination modality could provide the foundation for the accelerated identification of effective and safe multi-modality treatment algorithms for COVID-19 pneumonia. This article summarizes the insights and lessons learned from clinical immune-oncology trials as well as lung transplantation that are informing the clinical development of promising new strategies aimed at reducing the fatality rate in COVID-19.
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