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10.1080/22221751.2020.1787103

http://scihub22266oqcxt.onion/10.1080/22221751.2020.1787103
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suck abstract from ncbi


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pmid32573353      Emerg+Microbes+Infect 2020 ; 9 (1): 1537-1545
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  • Epidemiology and clinical course of COVID-19 in Shanghai, China #MMPMID32573353
  • Shen Y; Zheng F; Sun D; Ling Y; Chen J; Li F; Li T; Qian Z; Zhang Y; Xu Q; Liu L; Huang Q; Shan F; Xu L; Wu J; Zhu Z; Song Z; Li S; Shi Y; Zhang J; Wu X; Mendelsohn JB; Zhu T; Lu H
  • Emerg Microbes Infect 2020[Dec]; 9 (1): 1537-1545 PMID32573353show ga
  • Background: Novel coronavirus pneumonia (COVID-19) is prevalent around the world. We aimed to describe epidemiological features and clinical course in Shanghai. Methods: We retrospectively analysed 325 cases admitted at Shanghai Public Health Clinical Center, between January 20 and February 29, 2020. Results: 47.4% (154/325) had visited Wuhan within 2 weeks of illness onset. 57.2% occurred in 67 clusters; 40% were situated within 53 family clusters. 83.7% developed fever during the disease course. Median times from onset to first medical care, hospitalization and negative detection of nucleic acid by nasopharyngeal swab were 1, 4 and 8 days. Patients with mild disease using glucocorticoid tended to have longer viral shedding in blood and feces. At admission, 69.8% presented with lymphopenia and 38.8% had elevated D-dimers. Pneumonia was identified in 97.5% (314/322) of cases by chest CT scan. Severe-critical patients were 8% with a median time from onset to critical disease of 10.5 days. Half required oxygen therapy and 7.1% high-flow nasal oxygen. The case fatality rate was 0.92% with median time from onset to death of 16 days. Conclusion: COVID-19 cases in Shanghai were imported. Rapid identification, and effective control measures helped to contain the outbreak and prevent community transmission.
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19[MESH]
  • |China/epidemiology[MESH]
  • |Coronavirus Infections/complications/diagnosis/*epidemiology/therapy[MESH]
  • |Female[MESH]
  • |Follow-Up Studies[MESH]
  • |Health Status Indicators[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/complications/diagnosis/*epidemiology/therapy[MESH]
  • |Retrospective Studies[MESH]
  • |Time Factors[MESH]
  • |Treatment Outcome[MESH]
  • |Virus Shedding[MESH]


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