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10.1038/s41416-020-0948-x

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32572174!7307309!32572174
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suck abstract from ncbi


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pmid32572174      Br+J+Cancer 2020 ; 123 (5): 694-697
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  • Repurposing anticancer drugs for COVID-19-induced inflammation, immune dysfunction, and coagulopathy #MMPMID32572174
  • Saini KS; Lanza C; Romano M; de Azambuja E; Cortes J; de Las Heras B; de Castro J; Lamba Saini M; Loibl S; Curigliano G; Twelves C; Leone M; Patnaik MM
  • Br J Cancer 2020[Sep]; 123 (5): 694-697 PMID32572174show ga
  • Three cardinal manifestations of neoplasia, namely inflammation, immune dysfunction, and coagulopathy are also seen in patients with severe SARS-CoV-2 infection, providing a biological rationale for testing selected anticancer drugs for their ability to control the symptoms and/or modify the course of COVID-19.
  • |*Betacoronavirus[MESH]
  • |Adrenal Cortex Hormones/therapeutic use[MESH]
  • |Anticoagulants/therapeutic use[MESH]
  • |Antineoplastic Agents/pharmacology/*therapeutic use[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |Coronavirus Infections/*drug therapy/*immunology/physiopathology/virology[MESH]
  • |Drug Repositioning/*methods[MESH]
  • |Humans[MESH]
  • |Immunologic Factors/therapeutic use[MESH]
  • |Inflammation/drug therapy[MESH]
  • |Interleukin-6/antagonists & inhibitors[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*drug therapy/*immunology/physiopathology/virology[MESH]
  • |Programmed Cell Death 1 Receptor/antagonists & inhibitors[MESH]
  • |Protein Kinase Inhibitors/therapeutic use[MESH]
  • |SARS-CoV-2[MESH]
  • |Treatment Outcome[MESH]


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