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Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Chin+Med+Assoc 2020 ; 83 (9): 817-821 Nephropedia Template TP
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Pharmacological development of the potential adjuvant therapeutic agents against coronavirus disease 2019 #MMPMID32568969
Chen KH; Wang SF; Wang SY; Yang YP; Wang ML; Chiou SH; Chang YL
J Chin Med Assoc 2020[Sep]; 83 (9): 817-821 PMID32568969show ga
As the coronavirus disease 2019 (COVID-19, also called severe acute respiratory syndrome coronavirus-2) outbreak accelerates, vigorous and diverse efforts were made in developing treatment strategies. In addition to direct acting agents, increasing evidence showed some potential adjuvant therapies with promising efficacy against COVID-19. These therapies include immunomodulators (i.e. intravenous immunoglobulin, thymosin alpha-1, interleukin [IL]-6, tocilizumab, cyclosporine, thalidomide, fingolimod), Chinese medicines (i.e. glycyrrhizin, baicalin, Xuebijing), anti-vascular endothelial growth factors (bevacizumab), estrogen modulating drugs, statins, and nutritional supplements (i.e. vitamins A, B, C, D, E and zinc). This article reviewed the pharmacological development of potential adjuvants for COVID-19 treatment.