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10.1016/j.jiac.2020.06.010

http://scihub22266oqcxt.onion/10.1016/j.jiac.2020.06.010
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32565152!7290230!32565152
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suck abstract from ncbi


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pmid32565152      J+Infect+Chemother 2020 ; 26 (11): 1177-1180
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  • Clinical characteristics of the coronavirus disease 2019 (COVID-19) outbreak on a cruise ship #MMPMID32565152
  • Yoshimura Y; Sasaki H; Horiuchi H; Miyata N; Tachikawa N
  • J Infect Chemother 2020[Nov]; 26 (11): 1177-1180 PMID32565152show ga
  • BACKGROUND: A large COVID-19 outbreak occurred on the cruise ship Diamond Princess in February 2020. Little information has been reported about the clinical characteristics of the patients. METHODS: This single-center, retrospective, observational study was conducted in Yokohama, Japan. We included symptomatic patients who were infected on the ship and admitted to our hospital between 5 and 19 February 2020. All the cases were confirmed with SARS-CoV-2 infection by polymerase chain reaction (PCR). RESULTS: We confirmed 17 cases. The average age was 69 years; 10 patients were Asian and 7 were Caucasian. Eleven patients had one or more chronic diseases. The major symptoms were cough and fever. Chest computed tomography (CT) scans found bilateral ground-glass opacities predominantly in the peripheral area, which were similar to reports from cases in China. C-reactive protein (CRP) levels were higher in severe and critical cases than in mild to moderate cases. The moderate to severe cases reached symptomatic resolution; one of the three critical cases resulted in death due to multiple organ failure. SARS-CoV-2 was detected by PCR at an average of 7 days after symptomatic resolution. CONCLUSIONS: Cough and fever, increased blood CRP levels, and CT findings of bilateral ground-glass opacities predominantly in the peripheral lung were characteristic of the COVID-19 cases in this study. These findings were compatible with those of previous reports.
  • |*Travel-Related Illness[MESH]
  • |Aged[MESH]
  • |Betacoronavirus/genetics/*isolation & purification[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Clinical Laboratory Techniques/statistics & numerical data[MESH]
  • |Coronavirus Infections/diagnosis/*epidemiology/virology[MESH]
  • |Disease Outbreaks/*statistics & numerical data[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Japan/epidemiology[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/diagnosis/*epidemiology/virology[MESH]
  • |Polymerase Chain Reaction/statistics & numerical data[MESH]
  • |RNA, Viral/isolation & purification[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]


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