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10.4155/fmc-2020-0147 http://scihub22266oqcxt.onion/10.4155/fmc-2020-0147 32564623!7307730!32564623     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Future+Med+Chem 2020 ; 12 (17): 1579-1601 Nephropedia Template TP {{tp|p=32564623|t=2020. Tackling SARS-CoV-2: proposed targets and repurposed drugs |pdf=|usr=}}{{32564623}} gab.com Text Tackling SARS-CoV-2: proposed targets and repurposed drugs JO: Future Med Chem http://www.kidney.de/pget.php?&tw=1&pmid=32564623 #FOAvip The SARS-CoV-2 pandemic, declared as a global health emergency by the WHO in February 2020, has currently infected more than 6 million people with fatalities near 371,000 and increasing exponentially, in absence of vaccines and drugs. The pathogenesis of SARS-CoV-2 is still being elucidated. Identifying potential targets and repurposing drugs as therapeutic options is the need of the hour. In this review, we focus on potential druggable targets and suitable therapeutics, currently being explored in clinical trials, to treat SARS-CoV-2 infection. A brief understanding of the complex interactions of both viral as well as host targets, and the possible repurposed drug candidates are described with an emphasis on understanding the mechanisms at the molecular level. Twit Text FOAVip Tackling SARS-CoV-2: proposed targets and repurposed drugs ????Future Med Chem http://www.kidney.de/pget.php?&tw=1&pmid=32564623 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32564623 #FOAvip English Wikipedia <ref>{{Cite pmid|32564623}}</ref> Tackling SARS-CoV-2: proposed targets and repurposed drugs #MMPMID32564623 Joshi S; Joshi M; Degani MS Future Med Chem 2020[Sep]; 12 (17): 1579-1601 PMID32564623show ga The SARS-CoV-2 pandemic, declared as a global health emergency by the WHO in February 2020, has currently infected more than 6 million people with fatalities near 371,000 and increasing exponentially, in absence of vaccines and drugs. The pathogenesis of SARS-CoV-2 is still being elucidated. Identifying potential targets and repurposing drugs as therapeutic options is the need of the hour. In this review, we focus on potential druggable targets and suitable therapeutics, currently being explored in clinical trials, to treat SARS-CoV-2 infection. A brief understanding of the complex interactions of both viral as well as host targets, and the possible repurposed drug candidates are described with an emphasis on understanding the mechanisms at the molecular level. |*Drug Repositioning[MESH] |Animals[MESH] |Antiviral Agents/*therapeutic use[MESH] |Betacoronavirus/drug effects/growth & development[MESH] |COVID-19[MESH] |Coronavirus Infections/*drug therapy[MESH] |Humans[MESH] |Pandemics[MESH] |Pneumonia, Viral/*drug therapy[MESH] |Receptors, Virus/drug effects[MESH]Tackling SARS-CoV-2: proposed targets and repurposed drugs (epmc).pdf DeepDyve Pubget Overpricing