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10.1556/650.2020.31901 http://scihub22266oqcxt.onion/10.1556/650.2020.31901 32564002!ä!32564002 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 300.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 300.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 300.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 300.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 334.4 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 334.4 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 334.4 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Orv+Hetil 2020 ; 161 (27): 1111-1121 Nephropedia Template TP {{tp|p=32564002|t=2020. Az elso ket sikeres, convalescens friss fagyasztott plazmaval torteno terapia hazai alkalmazasa intenziv osztalyon kezelt, kritikus allapotu, COVID-19-fertozesben szenvedo betegekben: (A COVID-19-pandemia orvosszakmai kerdesei) |pdf=|usr=}}{{32564002}} gab.com Text Az elso ket sikeres, convalescens friss fagyasztott plazmaval torteno terapia hazai alkalmazasa intenziv osztalyon kezelt, kritikus allapotu, COVID-19-fertozesben szenvedo betegekben: (A COVID-19-pandemia orvosszakmai kerdesei) JO: Orv Hetil http://www.kidney.de/pget.php?&tw=1&pmid=32564002 #FOAvip INTRODUCTION: At present, neither specific curative treatment nor vaccines for novel coronavirus 2019 (COVID-19) are available. There is an urgent need to look for alternative strategies for COVID-19 treatment especially in the case of severe and/or critically ill patients with cytokine release syndrome (CRS). AIM: Convalescent plasma proved to increase survival rates in other severe viral infections. Therefore, convalescent plasma could be a promising treatment option for severe COVID-19 patients. METHOD: In our article, we present the first two critically ill Hungarian patients with COVID-19 infection treated with convalescent fresh frozen plasma. RESULTS: At the time of plasma therapy both patients were on mechanical ventilation and received antiviral agents and a full scale of supportive care. Each patient received 3 x 200 mL of convalescent plasma of recently recovered donors with sufficient novel anti-coronavirus IgG titers. Subsequent to convalescent plasma infusion, oxygenization improved and inflammatory markers decreased in both individuals. As compared to pretransfusion, lymphocyte counts increased and interleukin-6 level lessened. Both patients were weaned from mechanical ventilation within 2 weeks of treatment. No severe adverse effects were observed. CONCLUSIONS: Our experience indicates that convalescent plasma therapy is well tolerated and could potentially improve clinical outcomes. Optimal dose and timing as well as precise assessment of clinical benefit of convalescent plasma therapy will need further investigation in larger, well-controlled trials. This is the first report of the successful use of convalescent plasma in the treatment of critically ill patients with COVID-19 infection in Hungary. Orv Hetil. 2020; 161(27): 1111-1121. Twit Text FOAVip Az elso ket sikeres, convalescens friss fagyasztott plazmaval torteno terapia hazai alkalmazasa intenziv osztalyon kezelt, kritikus allapotu, COVID-19-fertozesben szenvedo betegekben: (A COVID-19-pandemia orvosszakmai kerdesei) ????Orv Hetil http://www.kidney.de/pget.php?&tw=1&pmid=32564002 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32564002 #FOAvip English Wikipedia <ref>{{Cite pmid|32564002}}</ref> Az elso ket sikeres, convalescens friss fagyasztott plazmaval torteno terapia hazai alkalmazasa intenziv osztalyon kezelt, kritikus allapotu, COVID-19-fertozesben szenvedo betegekben: (A COVID-19-pandemia orvosszakmai kerdesei) #MMPMID32564002 Bobek I; Gopcsa L; Reti M; Beko G; Hancz L; Lakatos B; Molnar E; Nagy S; Remenyi P; Sebestyen G; Sinko J; Szlavik J; Szolnoky M; Valyi-Nagy I Orv Hetil 2020[Jul]; 161 (27): 1111-1121 PMID32564002show ga INTRODUCTION: At present, neither specific curative treatment nor vaccines for novel coronavirus 2019 (COVID-19) are available. There is an urgent need to look for alternative strategies for COVID-19 treatment especially in the case of severe and/or critically ill patients with cytokine release syndrome (CRS). AIM: Convalescent plasma proved to increase survival rates in other severe viral infections. Therefore, convalescent plasma could be a promising treatment option for severe COVID-19 patients. METHOD: In our article, we present the first two critically ill Hungarian patients with COVID-19 infection treated with convalescent fresh frozen plasma. RESULTS: At the time of plasma therapy both patients were on mechanical ventilation and received antiviral agents and a full scale of supportive care. Each patient received 3 x 200 mL of convalescent plasma of recently recovered donors with sufficient novel anti-coronavirus IgG titers. Subsequent to convalescent plasma infusion, oxygenization improved and inflammatory markers decreased in both individuals. As compared to pretransfusion, lymphocyte counts increased and interleukin-6 level lessened. Both patients were weaned from mechanical ventilation within 2 weeks of treatment. No severe adverse effects were observed. CONCLUSIONS: Our experience indicates that convalescent plasma therapy is well tolerated and could potentially improve clinical outcomes. Optimal dose and timing as well as precise assessment of clinical benefit of convalescent plasma therapy will need further investigation in larger, well-controlled trials. This is the first report of the successful use of convalescent plasma in the treatment of critically ill patients with COVID-19 infection in Hungary. Orv Hetil. 2020; 161(27): 1111-1121. |COVID-19[MESH] |COVID-19 Serotherapy[MESH] |Coronavirus Infections/*therapy[MESH] |Critical Illness[MESH] |Humans[MESH] |Hungary[MESH] |Immunization, Passive[MESH] |Pandemics[MESH] |Pneumonia, Viral/*therapy[MESH]Az elso ket sikeres, convalescens friss fagyasztott plazmaval torteno (epmc).pdf DeepDyve Pubget Overpricing