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suck abstract from ncbi


10.1016/j.niox.2020.06.002

http://scihub22266oqcxt.onion/10.1016/j.niox.2020.06.002
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32562746!7837363!32562746
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suck abstract from ncbi

pmid32562746      Nitric+Oxide 2020 ; 102 (ä): 39-41
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  • Tackle the free radicals damage in COVID-19 #MMPMID32562746
  • Wu J
  • Nitric Oxide 2020[Sep]; 102 (ä): 39-41 PMID32562746show ga
  • COVID-19 is a severe pandemic which has caused a devastating amount of loss in lives around the world, and yet we still don't know how to appropriately treat this disease. We know very little about the pathogenesis of SARS-CoV-2, the virus which induces the COVID-19. However, COVID-19 does share many similar symptoms with SARS and influenza. Previous scientific discoveries learned from lab animal models and clinical practices shed light on possible pathogenic mechanisms in COVID-19. In the past decades, accumulated scientific findings confirmed the pathogenic role of free radicals damage in respiratory virus infection. Astonishingly very few medical professionals mention the crucial role of free radical damage in COVID-19. This hypothesis aims to summarize the crucial pathogenic role of free radical damage in respiratory virus induced pneumonia and suggest an antioxidative therapeutic strategy for COVID-19.
  • |*Betacoronavirus[MESH]
  • |*Pandemics[MESH]
  • |Acetylcysteine/therapeutic use[MESH]
  • |Animals[MESH]
  • |Antioxidants/therapeutic use[MESH]
  • |Ascorbic Acid/therapeutic use[MESH]
  • |Azithromycin/administration & dosage/pharmacology/therapeutic use[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |Clinical Trials as Topic[MESH]
  • |Coronavirus Infections/complications/drug therapy/*metabolism[MESH]
  • |Cytokine Release Syndrome/etiology/metabolism[MESH]
  • |Drug Therapy, Combination[MESH]
  • |Free Radicals/antagonists & inhibitors/*metabolism[MESH]
  • |Glutathione/therapeutic use[MESH]
  • |Humans[MESH]
  • |Hydroxychloroquine/administration & dosage/pharmacology/therapeutic use[MESH]
  • |Mice[MESH]
  • |Multiple Organ Failure/etiology/prevention & control[MESH]
  • |NF-E2-Related Factor 2/agonists[MESH]
  • |Nitric Oxide/metabolism[MESH]
  • |Orthomyxoviridae Infections/metabolism[MESH]
  • |Oxidative Stress[MESH]
  • |Pneumonia, Viral/complications/drug therapy/*metabolism[MESH]
  • |Reactive Oxygen Species/metabolism[MESH]
  • |SARS-CoV-2[MESH]


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