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10.1016/j.cca.2020.06.026

http://scihub22266oqcxt.onion/10.1016/j.cca.2020.06.026
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suck abstract from ncbi


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pmid32562665      Clin+Chim+Acta 2020 ; 509 (ä): 220-223
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  • Relationship between ABO blood group distribution and clinical characteristics in patients with COVID-19 #MMPMID32562665
  • Wu Y; Feng Z; Li P; Yu Q
  • Clin Chim Acta 2020[Oct]; 509 (ä): 220-223 PMID32562665show ga
  • OBJECTIVE: To explore ABO blood group distribution and clinical characteristics in patients with COVID-19. METHODS: The clinical data of 187 patients with COVID-19 seen between January 20, 2020 and March 5, 2020 at the First Hospital of Changsha were retrospectively analyzed. The differences in the ABO blood group distribution between COVID-19 patients and the control group (1991 cases) were analyzed. The relationship between blood type and clinical characteristics was analyzed. RESULTS: Of the 187 patients with COVID-19, 69 had type A (36.90%), 63 had type B (33.69%), 41 had type O (21.92%), and 14 had type AB blood (7.49%). The proportion of patients with type A blood in the COVID-19 group was significantly higher than that in the control group (36.90% vs. 27.47%, P = 0.006), while the proportion of patients with type O blood in the COVID-19 group was significantly lower than that in the control group (21.92% vs. 30.19%, P = 0.018). The risk of COVID-19 was higher for individuals with blood group A than for those with blood group O (OR = 1.849, 95% CI = 1.228-2.768, P = 0.003). The risk of COVID-19 was higher for patients with blood group A than for those with a blood group other than A (OR = 1.544, 95% CI = 1.122-2.104, P = 0.006). Patients with blood group O had a lower risk of COVID-19 than non-O blood group patients (OR = 0.649, 95% CI = 0.457-0.927, P = 0.018). The ABO blood group distribution was related to COVID-19 status. CONCLUSIONS: Patients with blood group A had an increased risk for infection with SARS-CoV-2, whereas blood group O was associated with a decreased risk, indicating that certain ABO blood groups were correlated with SARS-CoV-2 susceptibility. Blood type was related to some clinical characteristics of patients with COVID-19.
  • |*Betacoronavirus[MESH]
  • |ABO Blood-Group System/analysis/*blood[MESH]
  • |Adult[MESH]
  • |Blood Grouping and Crossmatching/*methods[MESH]
  • |COVID-19[MESH]
  • |Case-Control Studies[MESH]
  • |Coronavirus Infections/*blood/*diagnosis[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*blood/*diagnosis[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Factors[MESH]


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