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Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Mayo+Clin+Proc 2020 ; 95 (7): 1426-1429 Nephropedia Template TP
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A Framework for Evidence Synthesis Programs to Respond to a Pandemic #MMPMID32561147
Murad MH; Nayfeh T; Urtecho Suarez M; Seisa MO; Abd-Rabu R; Farah MHE; Firwana M; Hasan B; Jawaid T; Shah S; Torres Roldan V; Prokop L; Wang Z; Saadi SM
Mayo Clin Proc 2020[Jul]; 95 (7): 1426-1429 PMID32561147show ga
The coronavirus disease 2019 (COVID-19) pandemic requires making rapid decisions based on sparse and rapidly changing evidence. Evidence synthesis programs conduct systematic reviews for guideline developers, health systems clinicians, and decision-makers that usually take an average 6 to 8 months to complete. We present a framework for evidence synthesis programs to respond to pandemics that has proven feasible and practical during the COVID-19 response in a large multistate health system employing more than 78,000 people. The framework includes four components: an approach for conducting rapid reviews, a repository of rapid reviews, a registry for all original studies about COVID-19, and twice-weekly prioritized update of new evidence sent to key stakeholders. As COVID-19 will not be our last pandemic, we share the details of this framework to allow replication in other institutions and re-implementation in future pandemics.