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10.1007/s40520-020-01631-y http://scihub22266oqcxt.onion/10.1007/s40520-020-01631-y 32557332!7298699!32557332     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32557332&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Aging+Clin+Exp+Res 2020 ; 32 (8): 1599-1608 Nephropedia Template TP {{tp|p=32557332|t=2020. COVID-19 and the elderly: insights into pathogenesis and clinical decision-making |pdf=|usr=}}{{32557332}} gab.com Text COVID-19 and the elderly: insights into pathogenesis and clinical decision-making JO: Aging Clin Exp Res http://www.kidney.de/pget.php?&tw=1&pmid=32557332 #FOAvip The elderly may represent a specific cluster of high-risk patients for developing COVID-19 with rapidly progressive clinical deterioration. Indeed, in older individuals, immunosenescence and comorbid disorders are more likely to promote viral-induced cytokine storm resulting in life-threatening respiratory failure and multisystemic involvement. Early diagnosis and individualized therapeutic management should be developed for elderly subjects based on personal medical history and polypharmacotherapy. Our review examines the pathogenesis and clinical implications of ageing in COVID-19 patients; finally, we discuss the evidence and controversies in the management in the long-stay residential care homes and aspects of end-of-life care for elderly patients with COVID-19. Twit Text FOAVip COVID-19 and the elderly: insights into pathogenesis and clinical decision-making ????Aging Clin Exp Res http://www.kidney.de/pget.php?&tw=1&pmid=32557332 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32557332 #FOAvip English Wikipedia <ref>{{Cite pmid|32557332}}</ref> COVID-19 and the elderly: insights into pathogenesis and clinical decision-making #MMPMID32557332 Perrotta F; Corbi G; Mazzeo G; Boccia M; Aronne L; D'Agnano V; Komici K; Mazzarella G; Parrella R; Bianco A Aging Clin Exp Res 2020[Aug]; 32 (8): 1599-1608 PMID32557332show ga The elderly may represent a specific cluster of high-risk patients for developing COVID-19 with rapidly progressive clinical deterioration. Indeed, in older individuals, immunosenescence and comorbid disorders are more likely to promote viral-induced cytokine storm resulting in life-threatening respiratory failure and multisystemic involvement. Early diagnosis and individualized therapeutic management should be developed for elderly subjects based on personal medical history and polypharmacotherapy. Our review examines the pathogenesis and clinical implications of ageing in COVID-19 patients; finally, we discuss the evidence and controversies in the management in the long-stay residential care homes and aspects of end-of-life care for elderly patients with COVID-19. |*Betacoronavirus[MESH] |*Clinical Decision-Making[MESH] |*Coronavirus Infections[MESH] |*Pandemics[MESH] |*Pneumonia, Viral[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Aging[MESH] |COVID-19[MESH] |Cytokines/immunology[MESH] |Humans[MESH]COVID-19 and the elderly: insights into pathogenesis and clinical dec(epmc).pdf DeepDyve Pubget Overpricing