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Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Exp+Med 2020 ; 217 (8): ä Nephropedia Template TP
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The renin-angiotensin system: An integrated view of lung disease and coagulopathy in COVID-19 and therapeutic implications #MMPMID32556101
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J Exp Med 2020[Aug]; 217 (8): ä PMID32556101show ga
The renin-angiotensin system (RAS) has long been appreciated as a major regulator of blood pressure, but has more recently been recognized as a mechanism for modulating inflammation as well. While there has been concern in COVID-19 patients over the use of drugs that target this system, the RAS has not been explored fully as a druggable target. The abbreviated description of the RAS suggests that its dysregulation may be at the center of COVID-19.