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  • COVID-19: therapeutic approaches description and discussion #MMPMID32556054
  • Trindade GG; Caxito SMC; Xavier AREO; Xavier MAS; BrandAo F
  • An Acad Bras Cienc 2020[]; 92 (2): e20200466 PMID32556054show ga
  • COVID-19 emerged in December 2019 in China, and since then, has disrupted global public health and changed economic paradigms. In dealing with the new Coronavirus, SARS-CoV-2, the world has not faced such extreme global fragility since the "Spanish flu" pandemic in 1918. Researchers globally are dedicating efforts to the search for an effective treatment for COVID-19. Drugs already used in a clinical setting for other pathologies have been tested as a new therapeutic approach against SARS-CoV-2, setting off a frenzy over the preliminary data of different studies. This work aims to compile and discuss the data published thus far. Despite the potential effects of some antivirals and antiparasitic against COVID-19, clinical studies must confirm real effectiveness. However, non-pharmacological approaches have proven to be the most efficient strategy to date.
  • |Anti-Bacterial Agents/*administration & dosage/chemistry/pharmacology[MESH]
  • |Antiparasitic Agents/*administration & dosage/chemistry/pharmacology[MESH]
  • |Antiviral Agents/*administration & dosage/chemistry/pharmacology[MESH]
  • |Betacoronavirus/*drug effects[MESH]
  • |Coronavirus Infections/*drug therapy[MESH]
  • |Humans[MESH]
  • |Macrolides/*administration & dosage/chemistry/pharmacology[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*drug therapy[MESH]
  • |Serine Proteinase Inhibitors/*administration & dosage/chemistry/pharmacology[MESH]

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  • suck abstract from ncbi

    e20200466 2.92 2020