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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Nat+Rev+Immunol 2020 ; 20 (8): 455-456 Nephropedia Template TP
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Severe COVID-19 in the young and healthy: monogenic inborn errors of immunity? #MMPMID32555547
Zhang SY; Zhang Q; Casanova JL; Su HC
Nat Rev Immunol 2020[Aug]; 20 (8): 455-456 PMID32555547show ga
Severe COVID-19 is rare in previously healthy individuals who are less than 50 years of age, affecting probably no more than 1 in 1,000 such infected individuals. We suggest that these patients may become critically ill because of monogenic inborn errors that disrupt protective immunity to SARS-CoV-2.