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10.1542/peds.2020-1701

http://scihub22266oqcxt.onion/10.1542/peds.2020-1701
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32554811!ä!32554811

suck abstract from ncbi


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pmid32554811      Pediatrics 2020 ; 146 (3): ä
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  • Infant With SARS-CoV-2 Infection Causing Severe Lung Disease Treated With Remdesivir #MMPMID32554811
  • Frauenfelder C; Brierley J; Whittaker E; Perucca G; Bamford A
  • Pediatrics 2020[Sep]; 146 (3): ä PMID32554811show ga
  • We describe an ex-premature infant presenting with severe acute respiratory syndrome coronavirus 2 infection in the fifth week of life. In current reports, researchers indicate that acute symptomatic severe acute respiratory syndrome coronavirus 2 infection is relatively rare and much less severe than in adults. This case highlights that infection can be associated with life-threatening pulmonary disease in young infants and that infection can follow a similar disease course to that described in adults. We provide first data on the use of the novel antiviral remdesivir in a young child and an innovative approach to expedited approval from a multidisciplinary clinical team and bioethics committee for compassionate access to the drug.
  • |*Infant, Premature[MESH]
  • |Adenosine Monophosphate/*analogs & derivatives/therapeutic use[MESH]
  • |Alanine/*analogs & derivatives/therapeutic use[MESH]
  • |Antiviral Agents/*therapeutic use[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |Coronavirus Infections/*diagnosis/drug therapy[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Intensive Care Units[MESH]
  • |Intubation, Intratracheal/methods[MESH]
  • |Pandemics[MESH]
  • |Patient Discharge[MESH]
  • |Pneumonia, Viral/*diagnosis[MESH]
  • |Radiography, Thoracic/methods[MESH]
  • |Respiration, Artificial/methods[MESH]
  • |Severe Acute Respiratory Syndrome/diagnosis/*drug therapy[MESH]


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