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Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Pediatrics 2020 ; 146 (3): ä Nephropedia Template TP
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Infant With SARS-CoV-2 Infection Causing Severe Lung Disease Treated With Remdesivir #MMPMID32554811
Frauenfelder C; Brierley J; Whittaker E; Perucca G; Bamford A
Pediatrics 2020[Sep]; 146 (3): ä PMID32554811show ga
We describe an ex-premature infant presenting with severe acute respiratory syndrome coronavirus 2 infection in the fifth week of life. In current reports, researchers indicate that acute symptomatic severe acute respiratory syndrome coronavirus 2 infection is relatively rare and much less severe than in adults. This case highlights that infection can be associated with life-threatening pulmonary disease in young infants and that infection can follow a similar disease course to that described in adults. We provide first data on the use of the novel antiviral remdesivir in a young child and an innovative approach to expedited approval from a multidisciplinary clinical team and bioethics committee for compassionate access to the drug.